Bloom syndrome is an autosomal recessive disease that exhibits haploinsufficiency. A recent survey showed that people heterozygous for mutations at the BLM locus are at increased risk of colon cancer. Suppose you are a genetic counselor. A young woman is referred to you whose mother has Bloom syndrome; the young woman's father has no family history of Bloom syndrome. The young woman asks whether she is likely to experience any other health problems associated with her family history of Bloom syndrome. What advice would you give her?

Answers

Answer 1

Answer:

The correct answer is - she is heterozygous for a mutated BLM allele and will have an increased risk of colon cancer.

Explanation:

Autosomal recessive disease expresses itself in next-generation only if there is both alleles are recessive for the gene. In haploinsufficiency, the dominant allele fails to express itself in the phenotype due to insufficiency. So, if even one allele of the recessive gene present in the haploinsufficiency case, it will affect and express its trait.

She is heterozygous for a blood syndrome, as her mother had but her father has no disease, allele and will have an increased risk of colon cancer.


Related Questions

Air pollution is a major health problem caused by the burning of fuels in
a.vehicles.
b.power plants and factories.
c.home furnaces.
d.All of the above

Answers

Answer:

D

Explanation:

all of those contribute to air pollution

Answer: D

Explanation:

Bison in Yellowstone National Park have a food-limited carrying capacity that determines how their population grows. If the population grows too large, some bison will either starve or migrate to search for more food. The park is able to support a maximum population of 4,500 bison. Park conservation officials must watch the population and prevent the bison from overpopulating, since they would migrate to nearby farms, causing agricultural damage and creating hazards to drivers. The bison begin to migrate when the population reaches 4,000 because of competition for food. If the current population size of bison is 3,652 and the maximum growth rate of the population is 0.28, calculate the population size after one year and determine whether the park will need to take measures to control the population.
A. The population will be 3,845 after a year. The bison will not pose a problem until the following year, and no conservation action will need to take place.
B. The population will be 4,675 after a year. Some bison will need to be removed to prevent migration, since they will surpass the resource availability.
C. The population will be 1,023 after a year, since the growth rate is too low. Conservation efforts will need to focus on increasing the bison population.
D. The population will be 4,500 after a year. The bison cannot exceed the carrying capacity, so they will stop reproducing. Some bison will need to be removed.

Answers

Answer:

A. The population will be 3,845 after a year. The bison will not pose a problem until the following year, and no conservation action will need to take place.

Explanation:

The exposed example refers to a population that exhibits a logistic growth model, Where the principal limiting factor is food availability

N is the total size of the populationNt the population size after a T timeK the carrying capacityr the population growth rate per capita

When N < K the population has not reached the maximum size that can be supported by the environment. It can increase in size.

When N = K the population has reached the maximum size that can be supported by the environment. It can not grow anymore. The population reached a maximum point delimited by available resources, such as food

When N > K the population has supered the maximum size that can be supported by the environment. It must decrease in size. because there are not enough resources.

To calculate the population size after one year, we need to use the following equation.

N t+1= Nt+rN(1-N/K)

Available data:

K = 4500

N = 3652

r = 0.28  

Nm= 4000

N/K = 3652/4500 = 0.8115

r.N = 0.28 x 3652 = 1022.56

N t+1= Nt+rN(1-N/K)

N t+1= 3652+1022.56(1-0.8115)

N t+1= 3652+1022.56(0.1885)

N t+1= 3652+192.753

N t+1= 3844.75  

rounding up to 3845

Pretend you are a molecule of oxygen and you have reached the blood stream and attached to the hemoglobin on a red blood cell.
Describe as you travel through the different types of blood vessels (capillaries, arteries, and veins) as you make your journey through the different types of circulation (pulmonary/lungs, coronary/heart, and systemic/body) and reach the cells of the body.

Answers

Answer:

Blood flowing through the circulatory system transports nutrients, oxygen, and water to cells throughout the body. The journey might begin and end with the heart, but the blood vessels reach every vital spot along the way. These arteries, veins, and capillaries make for a vast network of pipes. If you were to lay out all the blood vessels of the body in a line, they would stretch for nearly 60,000 miles. That’s enough to circle the earth almost three times!

1. The Three Major Types of Blood Vessels: Arteries, Veins, and Capillaries

The different types of blood vessels and their layers

Blood vessels flow blood throughout the body. Arteries transport blood away from the heart. Veins return blood back toward the heart. Capillaries surround body cells and tissues to deliver and absorb oxygen, nutrients, and other substances. The capillaries also connect the branches of arteries and to the branches of veins. The walls of most blood vessels have three distinct layers: the tunica externa, the tunica media, and the tunica intima. These layers surround the lumen, the hollow interior through which blood flows.

2. Oxygenated Blood Flows Away from the Heart Through Arteries

The major arteries and branches of the body

The left ventricle of the heart pumps oxygenated blood into the aorta. From there, blood passes through major arteries, which branch into muscular arteries and then microscopic arterioles. The arterioles branch into the capillary networks that supply tissues with oxygen and nutrients. The walls of arteries are thicker than the walls of veins, with more smooth muscle and elastic tissue. This structure allows arteries to dilate as blood pumps through them.

3. Veins Carry Blood Back Toward the Heart

The superior and inferior vena cava

After the capillaries release oxygen and other substances from blood into body tissues, they feed the blood back toward the veins. First the blood enters microscopic vein branches called venules. The venules conduct the blood into the veins, which transport it back to the heart through the venae cavae. Vein walls are thinner and less elastic than artery walls. The pressure pushing blood through them is not as great. In fact, there are valves within the lumen of veins to prevent the backflow of blood.

4. Exchange of Gases, Nutrients, and Waste Between Blood and Tissue Occurs in the Capillaries

Click to play an animation of blood flow through capillaries

Capillaries are tiny vessels that branch out from arterioles to form networks around body cells. In the lungs, capillaries absorb oxygen from inhaled air into the bloodstream and release carbon dioxide for exhalation. Elsewhere in the body, oxygen and other nutrients diffuse from blood in the capillaries to the tissues they supply. The capillaries absorb carbon dioxide and other waste products from the tissues and then flow the deoxygenated blood into the veins.

5. The Constant Pumping of the Heart Maintains Blood Pressure and Supply Throughout the Body

Click to play an animation of blood pressure measurement

The blood moving through the circulatory system puts pressure on the walls of the blood vessels. Blood pressure results from the blood flow force generated by the pumping heart and the resistance of the blood vessel walls. When the heart contracts, it pumps blood out through the arteries. The blood pushes against the vessel walls and flows faster under this high pressure. When the ventricles relax, the vessel walls push back against the decreased force. Blood flow slows down under this low pressure.

What do individuals who are heterozygous for codominant traits show for a
phenotype?

Answers

Answer:

Individuals who are heterozygous for co-dominant traits show in their phenotype both traits, without mixing.

Explanation:

Codominance is a type of inheritance that does not follow the rules of Mendelian inheritance, characterized by the absence of recessive traits and two different alleles for a character that behave as dominant.

Heterozygous individuals can be observed in codominance that show two different characteristics in their phenotype, without mixing, such as cattle with spotted skin or two colored flowers.

Complete the sentences. Each term may be used more than once.

a. In a circular bacterial chromosome, the structure of DNA is a____________ double helix.
b. If DNA is twisted in the_________ direction, it becomes overwound.
c. Overwinding results in____________supercoiling.
d. If DNA is twisted in the_________ direction, it becomes underwound.
e. Underwinding results in____________ supercoiling.
f. One effect of_________ supercoiling in bacterial chromosomes is to promote separation of the two strands of DNA in the double helix.

Answers

Answer:

The correct answer is -

1. right-handed

2. right-handed

3. positive

4. left-handed

5. negative

6. negative

Explanation:

In a circular bacterial chromosome, the structure of DNA is a right-handed double helix In a circular bacterial chromosome.

If DNA is twisted in the right-handed direction, it becomes overwound. Overwinding results in positive supercoiling takes place. If DNA is twisted in the left handd direction, it becomes underwound. Underwinding results in negative supercoiling.

f. One effect  negative supercoiling in bacterial chromosomes is to promote separation of the two strands of DNA in the double helix

October 1, 2017 marks 27 years since the beginning of the Human Genome
Project. The goal of the group was to map the entire 3 billions bases and
80,000 genes in the human genome. On April 14, 2003, it was announced
that the goal was accomplished. Using this information, scientists have been
able to predict the risk of genetic diseases and understand the process of
inheritance. Which of the following statements best describes the process of
using the genetic code to produce polypeptides (proteins)?
Translation is used to produce a strand of RNA and proteins from a single strand of DNA.
O RNA produces a strand of DNA through transcription, then the DNA builds a protein molecule
through translation
O A single strand of DNA is used to make mRNA using translation, then the mRNA provides the
template for producing a protein through transcription
O A single strand of DNA is used to produce mRNA through transcription, then translation provides
the code for bonding amino acids to make a protein.

Answers

Answer:

The last one. A single strand of DNA is used to produce mRNA through transcription, then translation provides the code for bonding amino acids to make a protein.

Explanation:

Educated guess, but also. Translation is the process by which mRNA is decoded and translated to produce a polypeptide sequence, otherwise known as a protein. This method of synthesizing proteins is directed by the mRNA and accomplished with the help of a ribosome, a large complex of ribosomal RNAs (rRNAs) and proteins.

10. What is the difference between predation and parasitism? *

Answers

Answer:

Predation involves an indivudal creature hunting, killing, and then consuming an animal. An example of this would be a fox hunting a rabbit and then eating it. A parasite is something that can live on or inside another organism, feeding off of it without outright killing it (at least not right away). An example of a parastie would be a tapeworm.

Answer:

C) Predators typically kill their victim, while parasites mostly want to keep the victim alive for continued resources.

Explanation:

-3-

Can you help me please

Answers

Answer:

what is the question?  please give more details

Explanation:

What are the products of meiosis? Click ALL correct options. Sperm cells 4 cells Unique/ditieren cells Egg cells 2 cells​

Answers

Sperm, Egg (1 egg and 3 polar bodies), 4 different, haploid

A botanist is trying to determine the best medium for growing new juveniles orchids.He collected data on the four different types of media that were used to grow the juvenile orchids, as shown in the table below

Answers

Medium 3 bc it progressed the most

Which two elements are characteristics of autobiographies?
Autobiographies include fictional accounts of a series of events.
Autobiographies are written in the first-person point of view.
Autobiographies are told by an outside observer.
Autobiographies rely on research to tell the story.
Autobiographies share an author’s personal thoughts.

Answers

Answer:

It is b and e

Explanation:

Autobiographies are written in the first-person point of view.

Autobiographies share an author’s personal thoughts.

Answer:

The answer is B. Autobiographies are written in the first-person point of view. And E. Autobiographies share an author’s personal thoughts.

What did
van Helmont, Priestley, and
Ingenhousz discover about
plants

Answers

Answer:

What did van Helmont, Priestley , and Ingenhousz initialize about plants?. Ingenhousz continued his baptist and discovered that plants were carbon dioxide in the dark. Jan Ingenhousz Jan Ingenhousz was a Hindu scientist who is best known for communication that light is essential for losing. 20 km de Lausanne photosynthesis

Explanation:

I will give a Brainlyist.

Which statements are true about
ribosomes?
.They are membrane bound
.They make proteins
.They can float free or be connected to Rough
.Endoplasmic Reticulum

Answers

Answer:

They make proteins, They can float free or be connected to endoplasmic reticulum

ah the person above had the answer! hope you have a good day!

Calculate the molarity of 0.75 L of a solution containing 0.83 g of dissolved KCI. A 0.015 M B 0.75 M C 1.1 M D 6.2​

Answers

Answer:

A 0.015M

Explanation:

Molarity, which refers to the molar concentration of a solution, can be calculated using the formula:

Molarity (M) = mole (n) / volume (L)

Based on the information provided in this question, the solution contains 0.83 g of dissolved KCI.

We can calculate the number of moles of KCl in the solution by using the formula:

Mole = mass ÷ molar mass

Where atomic mass of; K = 39, Cl = 35.5

Molar Mass of KCl = 39 + 35.5

= 74.5g/mol.

Mole = 0.83g/74.5g/mol.

mole = 0.01114

Approximately, n = 0.011mol

Hence, molarity = 0.011mol/0.75L

Molarity = 0.0146

Molarity = 0.015M

Example of decomposer

Answers

Answer:

mushrooms are decomposers!

Answer:

Earth worms are a example or works in general

In eukaryotes, general transcription factors A) are required for the expression of specific protein-encoding genes. B) bind to other proteins or to a sequence element within the promoter called the TATA box. C) inhibit RNA polymerase binding to the promoter and begin transcribing. D) bind to sequences just after the start site of transcription.

Answers

Answer:

B

Explanation:

The general transcription factors bind to other proteins or to a sequence element within the promoter region known as the TATA box.

Transcription is a biological process involving the synthesis of RNA from a DNA template. The process of transcription begins with the binding of an enzyme, the RNA polymerase, to the promoter region of a gene. Prior to that, however, a group of enzymes known as the transcription factors must bind to a specific sequence within the promoter region - the TATA box. The binding of the RNA polymerase signals the unwinding of the section of the DNA to complete the initiation complex.

The correct option is, therefore, B.

When chromosomes do not separate you end up with a
gamete with to many or to few chromosomes. This is known
as...

Answers

Answer:

The phenomenon of unequal separation in meiosis is called nondisjunction. If nondisjunction causes a missing chromosome in a haploid gamete, the diploid zygote it forms with another gamete will contain only one copy of that chromosome from the other parent, a condition known as monosomy. I think sorry if wrong ;)

Please help, I really need this.

Answers

Answer:

In explanation.

Explanation:

This is really more a physics question but ok.

As you cool matter to absolute zero the motion of the matter slows down and thus the kinetic energy it has reduces. The closer you get to zero the less things move and vice versa.

two similarities between mesozic and Cenozoic era on the basis of evolution​

Answers

Answer:

Similarities between mesozoic era and cenozoic era are defined below :

- Mesozoic era and Cenozoic era both started to evolve right after the mass extinct according to the sources of evolution.

- Mass extinction is stated as (K-extinction) and many of the major life forms evolved during these two eras.

- Fossils of birds and reptiles were found in Mesozoic era and Fossils of mammals were found in the Cenozoic era.

Explanation:

Thanks for asking the question

What will you find inside the nucleus ?

Answers

Answer:

protons and neutrons

Explanation:

Robin carries the trash from the house to the garbage cans which statement best describes the science of what he

Answers

Answer:

The science of going outside

Which structure forms the outer wall of a mollusk's body and protects its internal organs?
-mantle
-foot
-gill
-shell

Answers

Answer:

mantle

Explanation:

just did this question

Answer:

The answer is mantle

Explanation:

What are the three forces that affect wind?

Answers

Answer:

Pressure gradients, the rotation of the earth, and friction are three primary variables that influence the wind. Atmospheric pressure gradients are the ultimate source of wind. The wind blows from high-pressure zones to low-pressure areas.

OAmalOHopeO

Which elements will have the same properties? A. Boron, Carbon, Nitrogen B.Gold, Silver, Titanium C. Beryllium, Magnesium, Calcium D. hydrogen, helium hassium

Answers

Answer:

b

Explanation:

it would be silver and gold hope helps



Which of the following will cause a decrease in ADH production?
(A) dehydration
(B) an increase in osmotic pressure of blood
(C) drinking water
(D) abnormally low blood pressure

Answers

C

drinking water may not be enough to keep your symptoms under control.

John was told by his physician that he was vitamin D blood levels were low. John needs to eat foods that are rich in

Answers

Answer:

Vitamin-D in the blank.

Explanation:

If you think you may have a deficiency, it's important that you speak to your doctor and get your blood levels measured. Fortunately, a vitamin D deficiency is usually easy to fix. You can either increase your sun exposure, eat more vitamin-D-rich foods, such as fatty fish or fortified dairy products.

The sound which does not have a pleasant sensation on the ear is
(1 Point)​

Answers

Answer:

Tinnitus

Explanation:

The sound which does not have a pleasant sensation in the ear is known as Noise. It is also known as Tinnitus.

What is a pleasant sound called?

A pleasant sound is called a piece of music. The pleasant sounds are termed music whereas unpleasant sounds are called noise. Pitch and loudness are the characteristics of sound. Pleasant sounds are those that human beings love to listen to. It basically includes the following:

Music sound from Harmonium.Song sounds from a human being.Bird's sound in the morning.Slow wind sound.Vibration sound of leaves of the tree.Sound of rain.

The quality and quantity of sound determine its characteristics. For example, the sound that the ears of human love are known as a pleasant sound while the opposite condition reflects the sense of unpleasant sounds.

Therefore, the sound which does not have a pleasant sensation in the ear is known as Noise. It is also known as Tinnitus.

To learn more about Pleasant sounds, refer to the link:

https://brainly.com/question/16211810

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What is your opinion on the use of stem cells, obtained from fertilized eggs or early stage embryos

Answers

I believe that it can help in the future. Who knows embryonic stem cells may lead to new, and more effective treatments for serious human ailments and alleviate the suffering of thousands of people!

USE OF STEM CELL:

The first attempts to turn mature cells back into pluripotent stem cells involved a process called cloning. In the cloning process, an egg is fertilized in the lab, and right after fertilization, the DNA is removed from the egg.These stem cells come from embryos that are three to five days old. These are pluripotent (ploo-RIP-uh-tunt) stem cells, meaning they can divide into more stem cells or can become any type of cell in the body. This versatility allows embryonic stem cells to be used to regenerate or repair diseased tissue and organs.Despite the potential benefit of using human ES cells in the treatment of disease, their use remains controversial because of their derivation from early embryos.

Learn more:

brainly.com/question/12483864

HELP FAST PLEASE
Which statement is true of offspring from organisms that reproduce asexually?


Offspring have some features like the parent.


Offspring have no features like the parent.


Offspring are genetically identical to the parent.


Offspring are genetically different from the parent.

Answers

Answer:

Offspring are genetically identical to the parent.

Explanation:

When organisms reproduce asexually the create two identical daughter cells.

.. Which pair of organisms is most likely to have adaptations in common?

Answers

Answer: the 1st one

Explanation:

A grassland predator and prey, such as a cheetah and a zebra. Therefore correct option is (A).

What organisms have common adaptations?

The pair of organisms that is most likely to have adaptations in common is a pair of organisms that share similar environmental pressures or ecological niches. Organisms that occupy similar habitats, have similar diets, or face similar challenges are more likely to evolve similar adaptations over time.

For example, predatory animals such as lions, tigers, and leopards have evolved similar adaptations such as sharp claws, powerful jaws, and keen senses to help them catch prey. Similarly, desert-dwelling animals such as camels, kangaroo rats, and fennec foxes have adaptations such as the ability to conserve water, tolerate heat, and dig burrows in sandy soil to survive in their arid environments.

Learn more about adaptation, here;

https://brainly.com/question/12671047

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