Glycogen synthetase kinase 3 beta is a protein kinase that has been implicated in many types of cancer. Depending on the cell type, the gene for glycogen synthetase kinase 3 beta (GSK38) can act ether as an oncogene or as a tumor suppressor. Which of the following best predicts how GSK 98 mutations can lead to the development of cancer? A Cells with inactive GSK 38 fail to trigger apoptosis. B Cells with inactive GSK 38 fail to proceed past the G2/M checkpoint. с Cells with overactive GSK 98 are more likely to repair DNA damage. Cells with overactive GSK 38 have longer cell cycles.​

Answers

Answer 1

Answer:

A Cells with inactive GSK 38 fail to trigger apoptosis

Explanation:

Apoptosis is defined as the process of programmed death cell. Tumor cells are capable of evading apoptosis, thereby leading to uncontrolled cell proliferation. Glycogen synthase kinase 3 (GSK-3) is a protein kinase that phosphorylates serine and threonine amino acid residues on different substrates, thus activating different signaling pathways and having different biological functions. The GSK-3-mediated phosphorylation on different substrates may lead to the activation or inactivation of apoptosis depending on the cell type. Thus, GSK-3 has a dual activity and functions as a tumor suppressor and oncoprotein.


Related Questions

how does climate and vegetation vary with latitude and elevation?​

Answers

Answer:

Climate and vegetation vary with latitude and altitude of an area. Latitude measures distance from the equator; altitude measures elevation above sea level. ... Deserts have little precipitation and little vegetation. They are found in tropical, temperate, and Polar Regions.

The climate and vegetation may significantly vary with the latitude and elevation. This is because as elevation increases the temperature decreases gradually that do not favor the actual growth of vegetation.

What is Climate?

Climate may be defined as a type of weather conditions that are persuading in any geographical location for a long period of time. In a more simple sense, it is characterized as the long-term pattern of weather in a particular area.

Latitude estimates the distance from the equator part of the earth and goes through the tropical, temperate, and colder regions of the earth. The vegetation is typically reduced with increasing the altitude or elevation with respect to the sea level.

It may also be noticed that the vegetation may alter with respect to the geographical location of the whole earth. It was never found to be completely absent.

Therefore, the climate and vegetation may significantly vary with the latitude and elevation.

To learn more about Vegetation, refer to the link:

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What is the role of photosynthesis and cellular respiration in the cycling of carbon; include the biosphere, atmosphere hydrosphere and geosphere?

Answers

Photosynthesis and cellular respiration are important components of the carbon cycle, in which carbon is exchanged among the biosphere, atmosphere, oceans, and geosphere through chemical, physical, geological, and biological processes.
Cellular respiration and photosynthesis are important parts of the carbon cycle. The carbon cycle is the pathways through which carbon is recycled in the biosphere. While cellular respiration releases carbon dioxide into the environment, photosynthesis pulls carbon dioxide out of the atmosphere. Photosynthesis and cellular respiration are important components of the carbon cycle, in which carbon is exchanged among the biosphere, atmosphere, oceans, and geosphere through chemical, physical, geological, and biological processes.

James examines a cell from an aloe plant and a cell from an owl feather. Which structure is found only in the cell from the aloe plant?
O A. chloroplast
OB. membrane
O C. mitochondrion
O D. nucleus

Answers

I’m thinking it’s A. Chloroplast

The chloroplast will only be found inside the Aloy plant while other structures will be shared by both cells. Option A is correct.

Difference between Plant and animal cells:Both plant cell animal cells are eukaryotic cells, but both have some unique structures.Plants have a cell wall but animals just have a cell membrane.A plant cell has a chloroplast for photosynthesis while an animal cell does not have a chloroplast.

Since owl is an animal and Aloy is a plant

Therefore, the chloroplast will only be found inside the Aloy plant while other structures will be shared by both cells.

Learn more about eukaryotic cells:

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which characteristic of living organisms is responsible for the production of oxygen in the leaf of a plant exposed to sunlight.

Answers

Answer:

Photosynthesis.

Explanation:

Photosynthesis is a characteristic of living organisms and it is typically responsible for the production of oxygen in the leaf of a plant exposed to sunlight. It is a chemical process used by plants to obtain food from sunlight.

All living organisms such as plants and animals require energy to function properly (life activities). Thus, the cell organelle where energy from nutrients is released is generally referred to as mitochondria. Animals and plants retrieve energy using mitochondria to do cellular respiration because they typically act like a digestive system by taking in nutrients, breaking them down and obtaining energy rich molecules for cell-life activities.

Cellular respiration can be defined as a series of metabolic reactions that typically occur in cells so as to produce energy in the form of adenosine triphosphate (ATP). During cellular respiration, high energy intermediates are created that can then be oxidized to make adenosine triphosphate (ATP). Therefore, the intermediary products are produced at the glycolysis and citric acid cycle stage.

3. Which tool do scientists use to classify plants that is based
on a series of paired characteristics?

observation power

dichotomous key

sketch book

plant classification

Answers

dichotomous key is the answer to your question
Dichotomous key is the answer

In the picture below, letter E represents:

A.substrate
B.enzyme
C.products
D.active site

Answers

Answer:

C.products is the answer.

Answer:

C. products

Explanation:

In the picture above, the letter E represents products.

In which direction is the wind likely to blow in the picture?
WATER
LAND
A. From the ocean to the land
B. From the sun to the land
O O O O
C. From the land to the ocean
D. From the land to the sun

Answers

Answer:

From the ocean to the land. just took the quiz.

Explanation: a p e x

During the day, the air above land in coastal regions warms up more quickly and starts to rise, hence option A is correct.

What is the direction of the wind?

As the warm air rises, a low-pressure region develops on the surface, enabling air from the sea to enter. As a result, the wind blows from the sea to the land during the day.

Predominant winds often blow east-west rather than north-south, especially in the afternoon when the land is being heated by the sun to its maximum.

the Coriolis effect causes wind systems to twist counterclockwise in the Northern Hemisphere and clockwise in the Southern Hemisphere most frequently in the spring and summer.

Therefore, because of the greater temperature differences between the ocean and nearby land, hence option A is correct.

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pls help I AM ON A TIMERR PLEASE

Answers

Answer:

They will move inside the cell cos the concentration inside the cell is too low

Explanation:

hope it helps

Answer:

2nd option

Explanation:

which phase of the cell cycle do cells go to when they are not ready to divide?

Answers

Answer:

Interphase

Explanation:

Answer:

interphase

Explanation:

I hope this helps!!!

Head injuries and spine injuries are very worrisome because:

A. Nerve cells go through cell division frequently

B. Skin cells go straight from First Growth to Synthesis phase

C. Skin cells go through cell division frequently

D. Nerve cells stay in G Zero phase after the first growth

Answers

D I’m guessing hgfdddfyjkbgftyuj

The life span of a star depends on:
plz hurry :)

Answers

Answer:

It's size

Explanation:

Answer:

mass

Explanation:

The lifetime of a star depends on its mass. Since stars spend about 90% of their lives burning hydrogen into helium on the main sequence, their main sequence lifetime is also determined by its mass.

Drop a paper a piece of thermocol and a piece of plastic from a height of 10 to 15 feet not the time for each object to hit the ground why does paper take more time than thermocol and thermocol more than the plastic piece make the paper to fell down in such a way that it should hit the ground before all of them and how does it happen

Answers

Answer:

The paper takes more time to fall than the piece of thermocol because it experiences a greater air resistance than the thermocol.

The thermocol takes more time than the piece of plastic because it experiences a greater air resistance.

The piece of paper can be made to fall faster than all of them and hit the ground faster by crumpling it and then giving it an initial velocity by throwing it downwards.

Explanation:

Objects falling freely due to the force of gravity alone are accelerated downwards at a constant value 9.8 m/s². This acceleration due to gravity is constant for all objects on the earth's surface and is independent of the mass of the objects.Therefore, when objects are release from the same height and allowed to fall freely under gravity, they are accelerated downwards to the same extent and are expected to hit the ground at the same time. However,due to the resistance of the air through which the objects are falling, they may hit the ground at different times depending on the shape of the falling objects.

Objects which have a greater surface area or volume per unit mass will experience a greater air drag or resistance and therefore, will take a longer time than objects of similar mass with a smaller volume or surface area.

The paper has a greater surface area per unit mass than the piece of thermocol, therefore, it takes more time to fall than the piece of thermocol because it experiences a greater air resistance than the thermocol.

The thermocol has a greater surface area per unit mass than the piece of plastic, therefore, it takes more time than the piece of plastic because it experiences a greater air resistance.

The piece of paper can be made to fall faster than all of them and hit the ground faster by crumpling it, thereby reducing its surface area per unit mass it and then giving it an initial velocity by throwing it downwards.

clouds form by the condensation of...

A: Water vapor
B: dust or dirt
C: heat
D: rain

Answers

Answer:

a

Explanation:

clouds form when water rises as water vapor and cools and condenses into clouds

The primary source of energy in most ecosystems is/are

Answers

Answer:

The Sun.

Explanation:

Energy reaches the Earth in the form of electromagnetic radiation.

Terrestrial solar radiation means solar radiation that reaches the Earth after passing through the Earth's atmosphere. About 97% of solar radiation reaches the Earth in the range of wavelengths 0.29 - 2.5 μm, and about 3% with wavelengths greater than 2.5 μm.

What does atomic number tell you about an atom? * Number of electrons in the nucleus Number of protons and neutrons in the nucleus Number of protons in the nucleus Number of electrons in the electron cloud around the nucleus *NEED ANSWER QUICKLY*

Answers

Answer:

Number of protons in the nucleus

Answer:

Number of protons in the nucleus

Explanation:

Name the nitrogen bases that pair up to make the rungs of the DNA ladder.

Answers

Answer:

Two of the bases are purines- adenine and guanine. The pyrimidines are thymine and cytosine.

HELP PLS!!!!!!
Polygenic traits are when one phenotype (trait) is controlled by several different genes. The provided example shows human skin color being controlled by 3 different genes. Describe one other trait (don't use skin color!) in any animal that you think could be a Polygenic trait, and explain why you think that it is (HINT: I did mention an example in class yesterday... lets SEE if you remember!).

Answers

This is sooooo hard but I’ll try

Osmosis is the movement of
across a memberane,
Food
water
oxygen
energy

Answers

Answer:

osmosis is the movement of a solvent across a membrane, so water

6 ways of expressing standard atmospheric pressure​(physical science)

Answers

6 ways of expressing standard atmospheric pressure include: millimetres (or inches) of mercury, pounds per square inch (psi), dynes per square centimetre, millibars (mb), standard atmospheres, and kilopascals.

Akshay decides one day to run a marathon without any training. After 10 minutes your lapsed and akashay, has run half a mile, he begins to get cramps in his thigh he's also breathing very rapidly what is causing the cramps on his legs?

Answers

Answer:

Lactic acid accumulation in the leg muscles

Explanation:

Muscle cramps are painful feelings caused by sudden contractions of the muscle. Cramps are caused by several reasons, however, based on the description of Akashay's activity, it is caused by ACCUMULATION OF LACTIC ACID in the leg muscles due to strenuous exercise.

According to this question, Akashay decided to run a marathon without any prior training. However, he started to get cramps on his thigh coupled with rapid breathing. There is a lack of oxygen in his cells, hence, anaerobic respiration was used leading to the formation of lactic acid. The buildup of lactic acid is what causes the painful sensation called CRAMP.

 The tool that measures air pressure is called what?

Answers

Answer: A barometer !

Explanation:

Hoped this helped ! :)

Compared with mitosis, the process of meiosis results in daughter cells that are-

A. haploid cells with the same number of chromosomes as the parent cells

B. haploid cells with a smaller number of chromosomes than the parent cells

C. diploid cells with a smaller number of chromosomes than the parent cells

D. diploid cells with the same number of chromosomes as the parent cells

Answers

Answer:

Explanation:

e

Answer: Haploid cells with a smaller number of chromosomes than the parent cell

Explanation: meiosis results in four daughter cells which are haploids. Haploids have half the number of chromosomes of the diploid parent cell.

5. Why do thorns and spines exist? *
O To stop animals from eating plants
To stop insects from pollinating
To stop people from looking at plants
O To help plants stay standing upright and give them their shape

Answers

Answer:

to stop animals from eating plants

Explanation:

the thorns and spines help protect the plant for example if we touch the plant it hurts same goes with animals

Answer:

A. To stop animals from eating plants

Help plzzzzzzzzzzzzzzzzz

Answers

Answer:

A) It helps to separate the chromosomes

Explanation:

An archer shot a 0.06 kg arrow at a target the arrow accelerated at 5,000 m/s squared to reach a speed of 50.0 m/s as it is left the bow.During this acceleration what was the net force to the nearest newton?

Answers

Answer:

the net force to the nearest newton is 300 N

Explanation:

The computation of the net force to the nearest newton is shown below:

According to the newton second law of motion, the force is proportional directly to the change rate in momentum

So,

Resulted force = mass × acceleration

F = 0.06 kg × 5,000 m/s

= 300 N

Hence, the net force to the nearest newton is 300 N

Answer:

300 N

Explanation:

Question 3 (2 points) According to Newton's 2nd Law, Force equals mass times acceleration. Sidney Crosby has a mass of 91kg and Claude Giroux has a mass of 85kg. If they both are accelerating at 20m/s2, which person will have the greater force when they collide? A.Sidney Crosby
B.Claude Giroux
C.They both will have the same force
D.Not enough information is given.​

Answers

Answer:Sidney Crosby

Explanation:

3. Which enzyme do scientists use to cut genes out of strands of DNA?

DNA polymerase

DNA ligase

restriction endonuclease

RNA polymerase

Answers

Answer:

Restriction Endonuclease.

How are genetic relationships represented?

Answers

Answer:

Genetic relationships are analysed based on the comparison of allelic identity or differences, regardless of the number of SNPs that differ between two alleles of a gene, which simplifies the analysis.

Explanation:

what are the briefly information about plant cell ​

Answers

Answer:

Plant cells are the basic unit of life in organisms of the kingdom Plantae. They are eukaryotic cells, which have a true nucleus along with specialized structures called organelles that carry out different functions. Plant cells have special organelles called chloroplasts, which create sugars via photosynthesis.

I am confusion can someone help?

The recommendation is that 9 year-old children get 11 hours sleep a night.

A telomere from a child that gets 11 hours sleep a night is 8,000 nucleotides long.

How long would you expect a telomere to be in a child that gets 9 hours sleep a night?

Answers

Answer:

I believe it would be 6,000

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