Melanie has had a recent cold with symptoms of runny nose, sneezing, coughing, congestion, and malaise. Today, she is concerned that she has a sharp pain in her chest. She goes to see her health care provider, and is diagnosed with costochondritis, an inflammation in the cartilage between the ribs. From your reading related to cellular injury and adaptations as well as inflammation, answer the following questions:

a. What anatomic problem most likely leads to costochondritis?
b. What is the injury in costochondritis?
c. What would the acute inflammatory response look like?

Answers

Answer 1

Answer:

a. Viral infections may lead to inflammation between the ribs (i.e., costochondritis)

b. Viral infection

c. Viral infection may lead to the influx of chemical mediators (cytokines), increased blood flow, and movement of plasma and white blood cells (leukocytes) from the blood into the injured site

Explanation:

Costochondritis is a painful condition caused by the inflammation of the cartilage that joins the ribs to the breastbone (this joint is known as the “costochondral joint”). Costochondritis is caused by inflammation of the costochondral joint, which may be triggered by multiple causes including, among others, viral/bacterial/fungal infections, exercise or strenuous activity, chest trauma, osteoarthritis, presence of tumors, etc. Acute inflammation is the immediate immune response of the body to harmful stimuli (e.g., viral infections), which is characterized by the increased movement of white blood cells (such as neutrophils and macrophages) that rapidly travel from the blood into the injured area. This plasma contains chemical mediators like pro-inflammatory cytokines which are secreted from immune cells (e.g., Th1 cells, CD4+ cells, macrophages) in order to promote inflammation.


Related Questions

Two different enzymes catalyze the same reaction and both exhibit the same Vmax. When Enzyme A was run with a 40 uM substrate, the initial rate (Vo) was 10 uM/min, and when g it was run with a 4 mM substrate, the Vo was 20 uM/min. Estimate the approximate Vmax and Km of Enzyme A. When Enzyme B was run with 80 uM substrate, the initial rate (Vo) was 10 uM per minute. Estimate the Km of Enzyme B.

Answers

Answer:

a) k_m = 4.08 uM

  V_{max} = 20.07 uM/min

b) k_m = 8.16 uM

Explanation:

Given that:

For Enzyme A:

the substrate concentration [S] = 40 uM

the initial velocity rate v = 10 uM/min

when it was 4mM, v = 20 uM/min

i.e.

at 4mM = 4000 uM;

Using Michealis -menten equation;

when v = 10

[tex]V = \dfrac{V_{max}[S]}{k_m+[S]}[/tex]

[tex]10 = \dfrac{V_{max}\times 40}{k_m + 40}[/tex]

[tex]10 (k_m + 40) = V_{max}40[/tex]

[tex]40V_{max} -10k_m = 400 --- (1)[/tex]

when v= 20

[tex]20= \dfrac{V_{max}\times 4000}{k_m + 4000}[/tex]

[tex]20 (k_m + 4000) = V_{max}4000[/tex]

[tex]4000V_{max} -20k_m = 8000 --- (2)[/tex]

equating equation (1) and (2):

[tex]40V_{max} -10k_m = 400 --- (1)[/tex]

[tex]4000V_{max} -20k_m = 8000 --- (2)[/tex]

let multiply equation (1) by 100 and equation (2) by 1

4000V_{max} - 1000K_m = 4000

4000V_{max} - 20 k_m = 8000    

  0        -980k_m = 4000

k_m = 4000/-980

k_m = 4.08 uM

replacing the value of k_m into equation (1)

40{V_max } - 10(4.08) = 400

40{V_max } - 40.8 = 400

40{V_max } = 400 +  40.8

40{V_max } = 440.8

V_{max} = 440.8/40

V_{max} = 11.02 uM/min

b)

Since V_{max} of A ie equivalent to that of B; then:

V_{max} of B = 11.02 uM/min

Here;

[S] = 80  uM

V = 10 uM/min

[tex]10 = \dfrac{11.02 \times 80}{k_m + 80 }[/tex]

10(k_m +80) = 881.6

10k_m = 881.6  - 800

10k_m = 81.6

k_m = 81.6/10

k_m = 8.16 uM

which organism in the food web might be found in the first tropic level of a food chain
cougar
mouse
acorns
coyote

Answers

Answer:

Acorns would be found at the first trophic level of a food chain.

Explanation:

14. What do the embryos of different vertebrate species have in common?​

Answers

Answer:

Similarities in embryos are evidence of common ancestry. All vertebrate embryos, for example, have gill slits and tails. Most vertebrates, except for fish, lose their gill slits by adulthood.

Explanation:

itz from gologolo lol I hope it helps uh

keep smiling #smilies

At her initial evaluation, Ms. Jones reports that she has lost 25 pounds over the past eight months despite an increase in her appetite. She complains of extreme fatigue, heart palpitations and irritability. Clinical observations reveal a protrusion of the eyeballs and hand tremors. You suspect that she might have:

a. hypothyroidism
b. diabetes mellitus
c. hypopituitarism
d. hyperthyroidism

Answers

Answer:

d. hyperthyroidism

Explanation:

Hyperthyroidism is a condition that occurs when the thyroid gland in our body secretes too much of the thyroxin hormone. Thyroid gland is a butterfly shaped gland that is located in our neck and it produces the hormone called thyroxin. Excess production of thyroxin leads to a condition named hyperthyroidism.

A person's metabolism increases when he or she is suffering from hyperthyroidism. One's weight is lost but the appetite increases. Other symptoms are extreme fatigue, irritability, heart palpitations, sweating and puffy eyes.

Thus in the context, Ms. Jones is suspect to have hyperthyroidism as she she is showing all the above symptoms.

plz explain in your own words
what are conjugated molecules????

Answers

In chemistry, a conjugated system is a system of connected p orbitals with delocalized electrons in a molecule, which in general lowers the overall energy of the molecule and increases stability. It is conventionally represented as having alternating single and multiple bonds

What is the role of RNA?

Answers

Answer:

It is the 1st one ○ to provide the original blueprint for protein production

Explanation:

RNA polymerase (green) synthesizes RNA by following a strand of DNA. RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription.

What is the complimentary dna strand for TCTTAAATGATCGAT

Answers

Answer:

AGAATTTACTAGCTA

Explanation:

The DNA strand pairs are:

Adenine (A) -- Thymine (T)

Cytosine (C) -- Guanine (G)

and vice versa.

The given strand:

TCTTAAATGATCGAT

Based on the given pairs above, your answer will be:

AGAATTTACTAGCTA

~

An organism that creates its own food is called:
A) a producer
B)a consumer
C)a carnivore
D) a decomposer

Answers

Answer:

a

Explanation:

Answer:

An autotroph is an organism that can produce its own food using light, water, carbon dioxide, or other chemicals. Because autotrophs produce their own food, they are sometimes called producers.Organisms are characterized into two broad categories based upon how they obtain their energy and nutrients: autotrophs and heterotrophs. Autotrophs are known as producers because they are able to make their own food from raw materials and energy. Examples include plants, algae, and some types of bacteria.

what will most likely happen if a population is large and no migration, mutation, or environmental change occurs?
1. natural selection will increase
2. nonrandom mating will start to occur
3. the rate of evolution will increase
4. gene frequencies will remain constant

Answers

4. Gene frequencies will remain constant

The Earth and the moon are kept in orbit by gravity and mass. Please select the best answer from the choices provided T F

Answers

Answer:

True

Explanation:

the Earth and the Moon are kept in orbit by gravity and mass.

Answer:

True (T)

Explanation:

Yeah, the Earth and the moon are kept in orbit by gravity and mass. Hence, this statement is True (correct).

economic importance of mosquito larva list five​

Answers

Explanation:

economic importance of mosquito larva are

Mosquito larvae grow by consuming microorganisms such as algae and microbes that decompose decaying plant material. Larval mosquitoes contribute to aquatic food chains by serving as food sources for many predators, including fish and birds.i hope it will help you

Describe the biome in which you currently live, or one in which you want to live, or have lived. What are the atmospheric conditions (wind pattern, humidity level, etc), solar intensity, and geographic/oceanographic features that have produced this unique ecosystem

Answers

Answer:

Southern Texas

Explanation:

The Wind pattern often is represented by the westerlies, which are the winds that flow in the northern latitude of the world. The humidity level in this zone varies from 10-20%, since we are in the desert we do not have much humidity, the solar intensity is high, often found in the 9-10 uv range, it is not advised to spend more than 10 minutes on direct sun without solar protection.  We have the Rio Grande to the south and some spare mountains.

Answer:

Southern Texas

Explanation:

Dehydration synthesis leads to WICH formation

Answers

Answer:

Polymers...........

Explanation:

In a Nitrogen metabolism study, the following data were obtained over the test period:

Nitrogen consumed 175 grams
Total Fecal N 35 grams
Metabolic Fecal N 10 grams
Total Urinary N 80 grams
Endogenous Urinary N 10 grams

Calculate:
a. Apparent Nitrogen digestibility (%)
b. True Nitrogen digestibility (%)
c. Nitrogen Balance (g)
d. Apparent Nitrogen Retention (%)

Answers

Answer:

a. 80%

b. 86%

c. 60 g

d. 34.29%

Explanation:

From the given information:

The apparent nitrogen digestibility (AD) is the ratio of the difference between the consumed nitrogen and fecal nitrogen to the consumed nitrogen.

Mathematically:

[tex]AD = \dfrac{consumed \ nitrogen - fecal \ nitrogen }{consumed \ nitrogen }[/tex]

[tex]AD = \dfrac{175 -35 }{175}[/tex]

AD = 0.8

To percentage, the apparent Nitrogen digestibility = 80%

b. True Nitrogen digestibility is calculated by the formula:

[tex]=\dfrac{consumed \ nitrogen - (fecal \ nitrogen -metabolic \ fecal)}{consumed \ nitrogen}[/tex]

[tex]= \dfrac{175 -(35-10)}{175}[/tex]

[tex]= \dfrac{175 -25}{175}[/tex]

= 0.86

= 86%

c. Nitrogen Balance = consumed Nitrogen - Fecal nitrogen - total uninary

Nitrogen Balance = (175 - 35 - 80) grams

Nitrogen Balance = 60 g

d. Apparent Nitrogen Retention (ANR) is computed as follows:

[tex]ANR = \dfrac{(consumed \ nitrogen-fecal\ nitrogen - total \ uninary )}{nitrogen \consumed }\times 100\%[/tex]

[tex]ANR = \dfrac{(175-35- 80 )}{175 }\times 100\%[/tex]

[tex]ANR = \dfrac{(60 )}{175 }\times 100\%[/tex]

ANR = 34.29%

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