The protein calcineurin binds to the protein calmodulin with an association rate of 8.9 × 103 M-1s-1 and an overall dissociation constant, Kd, of 10 nM. The dissociation rate kd is:_____. Please explain step by step.
A. 8.9 × 10^3 M-1s-1
B. 8.9 × 10^2 s-1
C. 1.1 × 10-10 s-1
D. 8.9 × 10-5 s-1

Answers

Answer 1

Answer:

D

Explanation:

From the information given:

Association rate [tex]K_a[/tex] = [tex]8.9 \times 10^3 M^{-1}s^{-1}[/tex]

dissociation constant [tex]K_D[/tex] = 10 nM

dissociation rate [tex]K_d[/tex] = ???

Using the following relation from equilibrium dissociation constant to determine the dissociation rate, we have:

[tex]K_D =\dfrac{ K_d}{K_a}[/tex]

[tex]K_d = K_D \times K_a[/tex]

[tex]K_d =(10*10^{-9} \ M) \times (8.9*10^3 \ M^{-1}{s^{-1})[/tex]

[tex]\mathbf{K_d =8.9*10^{-5} \ {s^{-1}}}[/tex]


Related Questions

I need help assay about Biopsychology can someone help me?

Answers

Core assumptions of the biopsychological approach

⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂

✍︎ The core assumption of a biopsychological approach is the fact that illness and health come as a result of a given interplay. In this case it should be known that this interplay revolves around factors like psychological, social and even biological aspects. Most notably, there is always an initiative and attempt to understand the aspect of psychopathology that is done through proper examining.

⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂⁂

꧁❁ ⁱ ʰᵒᵖᵉ ⁱᵗ ʰᵉˡᵖˢ ❁꧂

Review Questions
1. If a diploid eukaryotic cell contains 14 pairs of chromosomes for a total of 2n = 28, how
many chromosomes will be in the resulting products of cellular division if the cell
undergoes: mitosis?meiosis?
2. If a haploid eukaryotic cell contains 10 chromosomes for a total of n = 10. How many
chromosomes will be in the resulting daughter cells if this cell undergoes mitosis?
3. By what process do homologous chromosomes exchange portions of their DNA during
meiosis?
4. In what phase does the answer to #3 occur?
5. How many mature ova will be produced from each primary oocyte?
6. How many mature sperm will be produced from each primary spermatocyte?
7. Do the homologous chromosomes separate during meiosis I or meiosis II?
8. Do the sister chromatids separate during meiosis I or meiosis II?
9. What is a polar body?
10. List the phases of mitosis and briefly describe what happens in each phase:

Answers

Answer:

6==. During spermatogenesis, four sperm result from each primary spermatocyte, which divides into two haploid secondary spermatocytes; these cells will go through a second meiotic division to produce four spermatids

Toluene crosses pure lipid bilayers many hundreds of times faster than a related compound, phenylalanine. Suggest two different properties of these molecules that would account for this difference.

Answers

Answer:

The lipid bilayer is hydrophobic that is hydrophobic and it can easily cross the lipid bilayer.

Toulene is a hydrophobic and neutral molecule compound so it can easily pass through the bilayer. It is an aromatic compound with a methane group attached to the benzene ring. It is smaller in comparison to Phenylalanine.

Phenylalanine-- It is an amino acid with a benzene ring attached to it. This amino acid is less hydrophobic than the aliphatic amino acids. Because of its less hydrophobic nature, it travels slowly compared to Toluene. It is also larger and has amino and carboxyl groups attached to it. On the other hand, Phenylalanine is a polar compound which has -COOH and -NH2 group. which prevents its delay in its transport across the lipid bilayer.

Vasopressin works on

Answers

Answer:

To treat diabetes insipidus, which is caused by a lack of this naturally occurring pituitary hormone in the body. And used to treat or prevent certain conditions of the stomach after surgery or during abdominal x-rays.

Which of the following are NOT examples of data?
a.
facts
b.
figures
c.
theories
d.
measurements


Please select the best answer from the choices provided

A
B
C
D

Answers

Answer:

b

Explanation:

becusen yes

Answer:

Your answer would be C

Explanation:

Theories are not proven, they are simply ideas we come up with

Why do you think so many people seem to not care about the environmental issues we are facing?

Answers

Answer:

People are not aware of their causes and impacts.

Explanation:

First, people just seem to think that a little bit of harm won't impact the world at all, but that little bit for everyone adds up and the magnitude is a lot worse than people would imagine. Next, even if they/we do know the scale, they don't know how to help or are not interested enough to try and fix the problem. We all think that we won't be able to help enough to fix the issue.

Explain why it is not advisable for two sickle cell carriers to marry.​

Answers

Answer:

it results in pleiotropic effect and caused death of an offspring.


What is the dewpoint temperature when the dry-bulb temperature is 12°C and the wet-bulb
temperature is 4°C?
1. -9°C
2. 19°C
3. 8°C
4. 4°C

Answers

Answer:

-9°C That is the answer

Explanation:

hope it helps!

In the lung alveoli, the oxygen partial pressure is about 100 mm of mercury, or 0.13 Atm. If blood was solely composed of a saline solution (lacking any hemoglobin), oxygen equilibrates with the alveolar air to a concentration of about 3 mg/L or 0.093 mm). In oxygen-saturated blood, however, the O2 concentration is about 0.008 M (8 mm).

Required:
a. What is the Henry's Law constant for oxygen in saline?
b. What is the Henry's Law constant for oxygen in blood?
c. How much does the presence of hemoglobin enhance oxygen solubility in blood (i.e. what is the ratio in blood vs saline)?

Answers

Answer:

Picture is attached.

what type of properties change in a physical change?Give an example to support the answer?​

Answers

examples of physical changes in properties are melting, transition to a gas, crystallization, etc

When body temperature increases, thermoreceptors are stimulated and send nerve signals to the CNS. The CNS sends motor signals to sweat glands, which attempt to reduce body temperature. This is an example of a __________ reflex.a. organ.b. stretch.c. withdrawal.d. visceral.

Answers

Answer:

d. visceral.

Explanation:

The visceral reflex is one that happens autonomously in the body, aiming to maintain the balance of the body through quick responses to some specific impulses. An example of a visceral reflex is the reduction in body temperature with the release of sweat from the sweat glands.

The visceral reflexes are controlled by the autonomic nervous system, using the sympathetic and parasympathetic nervous system.


Match the rocks with the geological processes that create them.
igneous rocks
sedimentary rocks
metamorphic rocks
They are formed when liquid
magma cools and solidifles
beneath or above Earth's
surface.
They are molded by heat and
pressure deep inside Earth.
The heat comes from magma.
Pressure is exerted by the
motion of Earth's plates and
the weight of other rocks.
They are a result of weathering
and lithification, which is often
aided by the flow of water.

Answers

Answer:

Igneous rocks:

-They are formed when liquid magma cools and solidifies beneath or above Earth’s surface.

Sedimentary rocks:

-They are a result if weathering and lithification, which is often aided by the flow of water.

Metamorphic rocks:

-They are molded by heat and pressure deep inside Earth.

-The heat comes from magma.

-Pressure is exerted by the motion of Earth’s plates and the weight of other rocks.

Explanation:

These are all I can do. You gave 5 sentence choices right? Hope this helps!

Answer:

The answer is Igneous rocks, Metamorphic rocks, and Sedimentary rocks

Explanation:

(URGENT) Which of these statements is correct about the ocean waves? (100 points)


A) Wave 1 and Wave 2 have the same wavelength.

B) Wave 2 and Wave 3 have the same wavelength.

C) Wave 1 and Wave 2 have the same amplitude.

D) Wave 2 and Wave 3 have the same amplitude

Answers

Answer:

D

Explanation:

Wave 2 and Wave 3 have the same amplitude.

The most common Class II variant is the F508del variant, which is missing the 508th amino acid in the protein but has an otherwise normal sequence. Loss of this amino acid leads to misfolding of the protein, and the misfolded protein is not properly transported to the membrane. Based on this information, how many nucleotides are deleted in the CFTR allele encoding this variant?

Answers

Answer:

The correct answer is - 3 (two codons of 507th that are U, C, and the first nucleotide of 508th codon U).

Explanation:

Each amino acid is coded by a three-nucleotide base long codon. So in the case of the F508del variant, there is a deletion of three nucleotides that is encoded for phenylalanine amino acid.

In this isoleucine is encoded by 507th codon that is AUG and 508th codon is UUU codes for Isoleucine.

In this case, two codons of 507th are U, C, and the first nucleotide of 508th codon U. So overall three nucleotides are deleted in the F508del variant..

the prime mover of inspiration is the blank during normal quiet breathing expiration is a passive process as this muscle relaxes into its original dome shape. provide conditions when expiration becomes an active process or forced. explain

Answers

Answer:

The prime agonist of inspiration is the diaphragm muscle.

The conditions when expiration becomes an active process is : Emphysema, Pneumonia, Bronchitis.

-Expiration is the passive process as there is elastic recoil of lungs following inspiration without contraction of any muscles.

-The elastic fibers in alveoli are damages or filled with mucus and fluid in the disease such as conditions such as emphysema or pneumonia.

-Elastic recoil of lungs.

-Hence, muscle contraction is required to forcefully exhale the air from lungs. Internal intercostal muscles contract to pull the ribs downward and remove air from the lungs.

Which is true if energy in ecosystem

Answers

Explanation:

energy flows in only one direction through an ecosystem.

A male Bengal tiger is mated with a female Bengal tiger. Orange (O) dominates with(o)coat color. A secondary concern is mating Bengal tigers with alleles for white coats is an occurrence of weak wrist bones. Normal wrist bones (B) dominates weak (b). Both parents are heterozygous for both traits. What is the genotype of the parents? OoBb OOBb OoBB oobb

Answers

Answer: i dont know the answer

Explanation: bla bla bla bla bla

A scientist finds that another molecule has contaminated the mixture he is working with in the lab. When he analyzes its chemical structure, he finds that it contains uracil, is single stranded, and contains phosphate. What molecule has likely contaminated his mixture?


nucleotide

protein

DNA

RNA

Answers

Answer:

RNA

Explanation:

A ribonucleic acid (RNA) is one of two types of nucleic acid made up of nucleotide subunits. RNA is a single stranded molecule unlike DNA, which is double stranded. The nucleotide unit of nucleic acids is composed of a nitrogenous base (Adenine, Guanine, Cytosine and Thymine/Uracil), a pentose sugar (ribose and deoxyribose) and a phosphate group.

One of the key structural differences between RNA and DNA is that RNA contains URACIL nitrogenous base instead of THYMINE in DNA.

According to this question, a scientist finds that another molecule has contaminated the mixture he is working with in the lab. When he analyzes its chemical structure, he finds that it contains uracil, is single stranded, and contains phosphate. This illustrates that the contaminating molecule is a specific type of nucleic acid called RNA.

Answer:

rna

Explanation:

One of the livers main functions is to detoxify potentially toxic substances. Which organelle would you expect liver cells to have in abundance?

Answers

liver contain abundance of smooth endoplasmic reticulum

The negative effects of chemical control of weeds on rangelands

Answers

Answer:

Chemical residue remain on the vegetation.

Explanation:

The negative effects of chemical control of weeds on rangelands is that the chemical residue remain on the vegetation in rangeland which is dangerous for animals that feed on vegetation because the chemicals are toxic that cause serious damaged. Sometime the chemical also damaged the  weeds as well as vegetation of rangelands and also kill the beneficial insects that is needed by the plants present in rangelands.

Which best explains why sawdust burns more quickly than a block of wood of equal mass under the same conditions?
The molecules move more quickly in the sawdust than in the block of wood.
The pressure of oxygen is greater on the sawdust.
More molecules in the sawdust can collide with oxygen molecules.
Oxygen is more concentrated near the sawdust than the block of wood.

Answers

Which best explains why, under the same circumstances, sawdust burns more fast than a wood block of equivalent mass The molecules in the sawdust move more swiftly than those in the

A thermal burn is what?

An injury to the skin or other organic tissue known as a burn is one that is primarily brought on by heat, radiation, radioactivity, electricity, friction, or contact with chemicals. When hot liquids, heated solids, or flames come in touch with the skin and other tissues, part or all of the skin's cells are destroyed (flame burns)

What various sorts of Burns are there?

This tiny burn merely penetrates the skin's surface layer (epidermis). It might hurt and make you red. second-degree burn Both the epithelium and the next layer of skin are affected by this kind of burn (dermis). It could result in skin that is swollen, red, white, or patchy. The pain may become intense and blisters may form. Scarring may result from second-degree burns that are deep.

To know more about burns visit:

https://brainly.com/question/14152400

#SPJ1

Answer:

C.More molecules in the sawdust can collide with oxygen molecules.

Explanation:

real

Methylene blue can be used to stain DNA because it: (2 pts) forms ionic bonds with DNA changes the pH and therefore the structure of DNA makes DNA electron dense is an effective chemical fixative for cells is none of the above

Answers

Answer: Methylene blue can be used to stain DNA of a cell because it (forms ionic bonds with DNA).

Explanation:

To examine the components of a cell usually under a microscope, a stain or dye is being used to provide a clear and defined view of the area under study.

The deoxyribonucleic acid (DNA) of a cell which contains the hereditary information of the cell is located in the nucleus.

Methylene blue is a type of stain used by biologists which helps them view microscopic life in brilliant color. It is a cationic stain (positively charged blue dye); and binds to negatively charged parts of the cells, such as nucleus (DNA) and RNA in the cytoplasm (with lower affinity).

When DNA of a cell comes in contact with methylene blue on a slide, their opposite charges attract, causing methylene blue's "rings" to slide in between the "rungs" of the DNA "ladder." As a result, a rich blue stain that identifies the location of the cell nucleus can be observed. This produces a photosensitive reaction which can then be viewed under the microscope.

Therefore is can be used to stain the DNA of cell because it forms ionic bonds with DNA.

Why do scientists study seismographs?

Answers

To analyse mineral content from earth's crust

Answer:

To determine the location of an epicenter

Explanation:

A seismogram is a graph output by a seismograph ; a record of the shaking and vibration of the ground. By studying seismograms, scientists learn a lot about Earth's internal structure, like how fast the waves are moving and what type of material the waves are passing through.

The brain generally stores new information in its own different and unique netowrk but retrieves information by chunking it with information in netowkrs that contain similar characteristics or associations.

a. True
b. False

Answers

A would be the correct answer I believe

3 Peroxisomes are cellular organelles: A. with their own genome B. present only in protists C. without membrane OR D. collaborating with the nucleus O E site of some oxidation reactions

Answers

Answer:

E.site of some oxidation reactions

5. Shawn has a hypothesis that fungicides harm bee development. Using what you now know, describe an experiment to test Shawn’s hypothesis. Be sure your response includes what data should be collected and how you would collect it.

Answers

Answer:

Yes.

Explanation:

Yes, the fungicides harm bee development by causing changes in  behavior, immune health, and reproduction etc. For verifying this hypothesis, we have to take two environments, in one environment fungicides are applied to the plants while on the other environment, there is no fungicide applied to the plants. Th result shows that the bees are affected and act abnormal where fungicides are applied as compared to those bees which are normal in behaviour and other features.

Sell
BIOL-041-CR: Biology, Part 1 / Unit 1: Biology: The Study of Life /12: Cha
3. What is the name of the process whereby some organisms are able to keep their internal conditions suitable for living?
homeostasis
O reproduction
Ο Ο Ο Ο
O photosynthesis
O metabolism
4. In order to keep a steady population, animals in a population must reproduce at a rate that is at least equal to
O the rate of deaths
twice the number of births from the previous year
O the current population
O half the number of deaths

Answers

Answer:

3) homeostasis

Explanation:

is the process where by some oranism keep their internal conditions suitable for living

9.
I've been called the storage tank
By those with little taste
I'm a sack filled with water,
Food, enzymes, and waste
What am I?

A)Golgi Body (Complex)
B)Endoplasmic Reticulum
C)Nucleus
D)Ribosomes
E)Cell membrane
F)Cell wall
G)Vacuole
H)Lysosomes
I)Vesicles
J)Chloroplast
K)Chromosomes
L)Mitocondria

Answers

Answer: G)Vacuole

Explanation:

G)Vacuole is the answer. Hope this helps!

When the dry-bulb temperature is 22°C and the wet-bulb temperature is 13°C, the relative
humidity is
1. 10%
2. 33%
3. 41%
4. 59%

Answers

Answer:

33 percent is wright

hope it may help you

QUESTION 8
Which of the following occurs during cell division in prokaryotes?
Answers pick one:

Spindle fiber attachment
DNA replication
Histone production
All of the above
None of the aboveا

Answers

Answer:

Explanation:

Prokaryotes are single cell organisms, including bacteria, which divides through binary fission where the daughter cell is a complete replica of the father cell.

Eukaryotes are multi-cell organism, which reproduce either through mitosis or meoisis. Meoisis is sexual reproduction while mitosis is asexual reproduction

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