you are dispatched emergent to a possible carbon monoxide poisoning in a family residence. as you are questioning your patient, your partner is about to apply the pulse oximetry. you quickly remember in school you learned that cos affinity for hemoglobin compared to oxygen is times greater?

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I quickly remember in school I learned that CO's affinity for hemoglobin compared to oxygen is 200 times greater.

Carbon monoxide has a 200-fold higher affinity for hemoglobin than oxygen does. As soon as one molecule of carbon monoxide binds to hemoglobin, the hemoglobin-oxygen dissociation curve changes to the left, further increasing its affinity and significantly reducing the release of oxygen to the tissues.

The pH of tissue decreases and hydrogen ion concentration rises in carbon dioxide. Because of this, oxygen release to tissues is enhanced and hemoglobin's affinity for oxygen decreases. The lung experiences opposite changes.

Hemoglobin-bound carbon monoxide reduces the amount of oxygen carried to bodily tissues and essential organs like the brain and heart. The link between oxygen and hemoglobin is around 200 times weaker than the bond between carbon monoxide and hemoglobin.

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