Your friend works in a lab that examines microtubules. She decides to grow some microtubules in vitro. After growing some with normal (Alpha-Beta)‐tubulin dimers bound to GTP, she replaces them with only GMPCPP bound (Alpha-Beta)‐tubulin dimers. GMPCPP is analog of GTP that cannot be hydrolyzed to GDP
Will she observe dynamic instability in her GMPCPP‐bound microtubules? Explain.

Answers

Answer 1

Answer:

No, she will not observe dynamic instability

Explanation:

Microtubules are dynamic polymers formed by the assembly of α‐ and β‐tubulin, which alternate between growing and shrinking states. These states are regulated by the hydrolysis of GTP bound to β-tubulin. In consequence, the dynamic behavior of the microtubules depends on the binding and hydrolysis of GTP by β-tubulin, which alters the conformation of tubulin molecules. The Guanylyl 5′-α,β-methylenediphosphonate (GMPCPP) is a slowly hydrolyzing analog of GTP that binds to tubulin with an affinity four to eightfold lower than GTP, which is used to produce stable microtubules that resist their depolymerization. When microtubules are polymerized with GMPCPP, they do not undergo dynamic instability, because GTP hydrolysis is necessary for their switching behavior.


Related Questions

1. Discuss at least two attributes of a study that you would look for to determine whether or not it is rigorous.

Answers

Some of the aspects that help you determine whether a study is rigorous are questions and hypotheses that can be answered, adequated method use, and bibliography.

Rigorous is a term that refers to a quality that focuses on accuracy and precision to comply with norms, precepts, and pre-established rules. This term is widely used in science to refer to the precision of a study or investigation.

Therefore, when it is established that a study is rigorous, its attributes must be taken into account, such as:

- Questions and hypotheses that can be answered: This aspect refers to the investigator having the ability to limit his study so that it is appropriate to do so and does not include too much information that makes his study "impossible".

- Adequated methods use: This refers to using the appropriate methods to reach feasible conclusions, for example, methods of observation, deduction, induction, among others.

- Bibliography: This refers to the research or study being supported by reliable sources so that it is as accurate as the information it provides.

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Imagine you found S. aureus to be resistant to Penicillin by Kirby Bauer analysis, but susceptible to Penicillin treatment in liquid culture (in other words, a MIC was determined). Which of the following are possible explanations for this inconsistency?

a. The concentration of Penicillin was higher in the Penicillin antibiotic disk than that used in liquid culture treatment.
b. The Penicillin disks used for Kirby Bauer analysis were expired/no longer active.
c. The concentration of bacteria was lower on the Mueller Hinton plate for Kirby Bauer analysis than that used in liquid culture treatment

Answers

The answer is definitely the concentration

What is the role of pitutary gland in puberity

Answers

Answer:

Puberty has begun. The trigger for puberty in both boys and girls is the production of 'gonadotrophin releasing hormone' (GnRH) from a part of the brain called the hypothalamus. This hormone stimulates the pituitary gland to release two hormones, Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH).

Explanation:

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Answer:

the gland produce hormones that help to regulate growth and body functions.

Partes del sistema linfatico

Answers

Answer:

Explanation:

Le parti principali del tessuto linfatico sono il midollo osseo, la milza, la ghiandola del timo, i linfonodi, i linfonodi e le tonsille.

Which is the only element in group 1 on the periodic table that forms covalent bonds?

hydrogen
lithium
potassium
sodium
.

Answers

Answer:

Hydrogen

Explanation:

Hydrogen is the only nonmetal in group 1, therefore it is the only element in group 1 that forms a covalent bond.

Answer:

A.

Explanation:

Cells dispose of large waste molecules through a process called

osmosis.
diffusion.
exocytosis.
endocytosis.

Answers

Cells dispose of large waste molecules through a process called exocytosis.

Exocytosis is the process through which cells can eliminate wastes, which might be useless or toxic, to the extracellular space.

-------------------------------

The endocytosis and exocytosis process refers to molecules transport mediated by vesicles.

Exocytosis occurs from and into the cell and needs energy to happen because it is active transport.Exocytosis involves vesicles or vacuoles. Vesicles or vacuoles can carry substances destined for exportation or cellular wastes. Wastes may be large molecules that result useless for the cells or that might be toxic. During the exocytosis process

         1) excretion compounds of varying nature accumulate within the  

             vesicle

         2) The vesicle migrates toward the cellular surface.

         3) Once in the surface, the vesicle's membrane fuses with the cellular

             membrane, and its content is expelled from the cell to the  

             extracellular space.

         4) Vesicle membrane remains fused to the cell membrane until it is

              reused during endocytosis events.

------------------------------

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what is the difference of biology and human and social biology?????

Answers

Answer:

Man's health (human biology) affects and effects change on society (social biology). Human and social biology scrutinizes the human body, disease, health, nature and the environment's influence on biology.

Answer:

Man's health (human biology) affects and effects change on society (social biology). Human and social biology scrutinizes the human body, disease, health, nature and the environment's influence on biology.

Hope this helped! Good luck! :)

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100 POINTS!!!!!!
The theories surrounding the formation of our solar system are based on many

biased opinions
incorrect facts
non-testable data
scientific investigations

Answers

scientific investigations is the correct thing

Answer:

"scientific investigations."

M. magneticum can only survive in low-oxygen environments, which are typically found near the bottom of bodies of water.

a. True
b. False

Answers

b good luck on future quizzes !!

Question 12 of 25
How are photosynthesis and cellular respiration related?
A. The products of photosynthesis are the reactants of cellular
respiration.
O B. Cellular respiration is the process animals use to produce glucose,
while photosynthesis is the process plants use to produce
glucose.
C. Cellular respiration provides the energy for photosynthesis.
D. Photosynthesis produces water molecules, while cellular
respiration splits water molecules apart.
SUBMIT

Answers

Answer:

A) The products of photosynthesis are the reactants of cellular

respiration.

Explanation:

Photosynthesis converts carbon dioxide and water into oxygen and glucose, so that cellular respiration converts oxygen and glucose into water and carbon dioxide.

How many newborn would you expect to have cystic fibrosis in a population of 10,000 people?

Answers

Answer:

6

Explanation:

10,000 people divided by 1700 is about 5.8

round 5.8 to a whole number at you will expect 6 people to have cystic fibrosis in a population of 10,000 people

Please add the missing term:
Species -> Population -> Community
-> Ecosystem -> Biome ->
A. Ecology
B. Life Bubble
C. Hydrosphere
D. Biosphere
Copyright 2003 - 2021 Acellus Corporational

Answers

Answer:

Biosphere hope its a good one

The largest population of a particular species that an ecosystem can support
is the ecosystem's
O A. biome
O B. biodiversity
O C. carrying capacity
O D. keystone species
VOU
O Type here to search
D
SA

Answers

The largest population of a particular species that an ecosystem can support is the ecosystem's carrying capacity.

What is a carrying capacity?

Carrying capacity in ecology refers to the number of individuals of a particular species that an environment can support.

Every ecosystem has a maximum number of biotic components that it can support to ensure the sustainability of its resources.

Therefore, the largest population of a particular species that an ecosystem can support is the ecosystem's carrying capacity.

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What is the frequency of a wave that has a wavelength of .20 m and a speed of 22 m/s

Answers

Answer:

110 Hz

Explanation:

Find the frequency of the wave using the formula, frequency = speed / wavelength.

Plug in the speed and wavelength, and solve:

frequency = speed / wavelength

frequency = 22 / 0.2

frequency = 110

So, the frequency of the wave is 110 Hz

Una de las aplicaciones más importa del electromagnetismo son

Answers

Answer:

Las principales aplicaciones del electromagnetismo se emplean en: La electricidad. El magnetismo. La conductividad eléctrica y superconductividad.

Explanation:

RNA thường bắt đầu bằng base nào

Answers

Answer:

Xin lỗi vì bản dịch xấu.  Nó được tạo thành từ các căn cứ adenine, cytosine, guanine và uracil.

Explanation:

So với RNA, DNA có thymine thay vì uracil trong một phân tử di truyền polymer.

HELP PLEASE FAST ASAP PLEASE HELP

Answers

Answer:

D. Their ability to replicate very fast and natural mutations combine to allow them to evolve rapidly

Explanation:

They develop mutations in their DNA that can be resistant to the drugs given.

Which of the following statements best describes one difference between transcription and translation?

Answers

The answer is the first one


reptilesimprovements over amphibians​

Answers

The person above me is correct

What type of cells are produced during
meiosis?

A. asexual cells
B. diploid cells
C. division cells
D. haploid cells

Answers

Answer:

D. haploid cells

Explanation:

Meiosis results in 4 gametes with 23 unpaired chromosomes, making them haploid cells.

Which of the following describes the product of Meiosis?
A. 4 genetically identical diploid cells
B. 4 genetically unique diploid cells
C. None of these are correct
D. 2 genetically unique haploid cells

Answers

Answer:

C

Explanation:

meiosis made 4 haploid daughter cells, with 1 round of dna replicates and followed by 4 division of haploid daughter cells

Explain why the lack of surfactant would result in respiratory distress. Furthermore, what type of acid-base disorder might she develop and how would her body compensate. Be detailed in your explanation and support your answer with facts from your textbook, research, and articles from scholarly journals.

Answers

Answer:

Due to lack of expansion of lungs.

Explanation:

The lack of surfactant compound would result in respiratory distress because Surfactant enables the lungs to expand more easily which allows easiness in respiration. Without surfactant, the air sacs in the lungs will collapse very easily. This collapse leads to decreased amounts of air or oxygen in the lungs which makes it very difficult for the people or infant to breathe.

PLEASE HELP ME!!!! I am stuck.
The frequency of tasters and nontasters of PTC varies among populations. (Answer ALL questions)
- In population A, 94 percent of people are tasters (an autosomal dominant trait)
and 6 percent are nontasters.
- In population B, tasters are 75 percent and nontasters 25 percent.
- In population C, tasters are 91 percent and nontasters are 9 percent.

1. Calculate the frequency of the dominant (T) allele for PTC tasting in population A.
2. Calculate the frequency of the recessive (t) allele for nontasting in population A.
3. Calculate the frequency of the dominant (T) allele for PTC tasting in population B.
4. Calculate the frequency of the recessive (t) allele for nontasting in population B.
5. Calculate the frequency of the dominant (T) allele for PTC tasting in population C.
6. Calculate the frequency of the recessive (t) allele for nontasting in population C.
7. Assuming that Hardy-Weinberg conditions apply, determine the TT frequency in population A.
8. Assuming that Hardy-Weinberg conditions apply, determine the Tt frequency in population A.
9. Assuming that Hardy-Weinberg conditions apply, determine the tt frequency in population A.
10. Assuming that Hardy-Weinberg conditions apply, determine the TT frequency in population B.
11. Assuming that Hardy-Weinberg conditions apply, determine the Tt frequency in population B.
12. Assuming that Hardy-Weinberg conditions apply, determine the tt frequency in population B.
13. Assuming that Hardy-Weinberg conditions apply, determine the TT frequency in population C.
14. Assuming that Hardy-Weinberg conditions apply, determine the Tt frequency in population C.
15. Assuming that Hardy-Weinberg conditions apply, determine the tt frequency in population C.

Answers

Answer:

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fk.ydj.td.jtd.sjtd

ktdfylluflyfulgñugñugñugñuguñgpi

Explanation:

hhm y chupapico

What is
FOOD & NUTRITON 1​

Answers

Answer:

1 How food keeps us healthy. Food is needed for energy and nutrients to exist, it provides energy for work, and warmth for the body. Everybody also needs food to build, maintain and repair their body. It is also required for control of body processes and for protection against disease and infections.

Answer:

Any nutritious substance that people or animals eat or drink or that plants absorb in order to maintain life and growth.

Nutrition is the biochemical and physiological process by which an organism uses food to support its life.

What is the best way to ensure that results of a study are generalizable to a population?

By making sure to use as many participants as possible

By making sure the results are significant

By making sure to use an equal number of men and women

By using random assignment

By using a random selection of people in that population

Answers

The best way to ensure that results of a study are generalizable to a population is by using a random selection of people in that population

The goal of every research experiment is to obtain results that are  generalizable to a whole population.

This is achieved by the method of random selection. In random selection, members of the of the population are selected in such a way that is representative of the entire population. If for instance, I want to study a school having six classes which comprises of boys and girls. There are 700 students in the school and I need only 180 students to participate in a study whose results will be extrapolated to all the 700 students. I can decide to randomly select 15 boys and 15 girls from each class to participate in the study. This is an example of random selection.

In this way, the results obtained from the study is reflective of the whole population even though only a sample of the population actually participated in the study.

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what gender of offspring are most often affected by sextinked inheritance?-What gender-are-usmally-carriers-of the trait?

-males, males
-males, females
-females, females
-females, males O O

Answers

Answer:

female, female

Explanation:

this is because sex-linked characters are normally borne in the X-chromosome

which of the specific classification is the specific organism found

Answers

Answer:

Species are as specific as you can get. It is the lowest and most strict level of classification of living things. The main criterion for an organism to be placed in a particular species is the ability to breed with other organisms of that same species.

Under normal conditions the sympathetic division is usually active in the body resting heart rates are influenced by nor epinephrine the parasympathetic system keeps heart rate lower than the heart would beat on its own. all of the above are true

Answers

Answer:

the parasympathetic system keeps heart rate lower than the heart would beat on its own.  

Explanation:

The parasympathetic nervous system (PNS) is one division of the autonomic nervous system. The vagus (parasympathetic) nerves that innervate the heart release acetylcholine in order to slow the heart rate by decreasing the slope of the pacemaker potential. Acetylcholine activates a type of G-coupled protein receptor known as muscarinic receptors, allowing for a parasympathetic reaction in the cardiovascular system (where these receptors are expressed), and thereby decreasing cardiac output by inhibiting heart rate. During rest, PNS predominates and controls the heart rate at a resting rate of 65-80 beats/minute (bpm), if parasympathetic nerves to the heart are cut, then the heart beats at its own rate of about 100 bpm.

What type of factors would have the
greatest influence on a densely
populated area?
A. drought
B. density-dependent factors
C. density-independent factors

Answers

A)Density-dependent factors

what are microorganisms? write the living and non living characteristics of virus. ​

Answers

Answer:

In easy word ......the virus or organism that can only be seen through Microsoft is called microorganisms

Explanation:

Those organisms which cannot be seen under naked eyes and require microscope to be seen are called micro-organisms.

The main living character of the viruses is they contain DNA or RNA as the genetic material. The main non-living character of the viruses is they can be crystallized like other chemicals

Hope ,this helps you!

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what is Thomas Paine's tone in "The Crisis, No. 1"? Imagine youre on a camping trip with a group of friends. One friend (played by your partner) pulls a bottle of liquor out of a backpack and starts to pass it. Your entire group of friends drinks from the bottle before passing it to you. Begin your dialogue with your friend by assertively refusing the drink. You may explain your refusal in any way that makes the most sense to you. Your friend should then respond by trying to persuade you. Continue this role-playing until each of you has had a few opportunities to speak. The average weight of a professional football player in 2009 was pounds. Assume the population standard deviation is pounds. A random sample of professional football players was selected. Required:a. Calculate the standard error of the mean.b. What is the probability that the sample mean will be less than 230 pounds?c. What is the probability that the sample mean will be more than 231 pounds?d. What is the probability that the sample mean will be between 248 pounds and 255 pounds? i need help in biology questions please G10? How many moles of Ba(OH)2 are present in 205 mL of 0.600 M Ba(OH)2? The predominant consequence to an individual who is genetically deficient in liver fructose 1,6-bisphosphatase would beA. Inability to metabolize fructose.B. a lowered yield of ATP production per mole of glucose metabolized.C. a failure to split fructose bisphosphate into triose phosphates.D. a failure to resynthesize glucose from lactic acid. describe the concept of development in brief Nadia is ordering cheesecake at a restaurant, and the server tells her that she can have up to five toppings: caramel, whipped cream, butterscotch sauce, strawberries, and hot fudge. Since she cannot decide how many of the toppings she wants, she tells the server to surprise her. If the server randomly chooses which toppings to add, what is the probability that Nadia gets just caramel, butterscotch sauce, strawberries, and hot fudge List the three ways in which humans interact with their environment.a.b.C. In 25 words or fewer, define ethics.Type answer here...Word Count: 25 The equation of a line is (3)/(5)x+(1)/(3)y=(1)/(15) . The x-intercept of the line is , and its y-intercept is . What is the measure of cartoon analysis in an essay format Consider this statement about the theme of this myth:What appears to be a problem may actually be a benefit.Click or tap ONE set of underlined sentences on page 1 or 2 that provides support for this theme. Classify the descriptions as pertaining to nucleosides, nucleotides, or both nucleosides and nucleotides. a. Do not contain a phosphate group b. The product when a base bonds to carbon 1 of ribose or deoxyribose c. Contain a base and a monosaccharide monosaccharide, and a phosphate group and Associates, a law firm, paid $30000 for 12 months' rent in advance on October 1 of the current year. The company's fiscal year-end is December 31. Prepare the journal entries for the rent payment on October 1 and the necessary adjusting journal entry on December 31. Omit explanations solve for x. solve for x. solve for x. Help me please 9) Determine which sides, if any, of the figures are parallel, perpendicular, or neither.Rectangle BACD has coordinate B(-4,-3), A(-1, -7),C(3,-4), and D(0,0). In an experiment to investigate a factor affecting photosynthesis, a leaf of a potted plant which had been kept in the dark overnight was covered with aluminum foil as shown in the diagram below 1. Aluminium foil The set up was kept in sunlight for three hours after which a food test was carried out on the leaf. (a) Which factor was being investigated in the experiment? b) What food test was carried out? (i) State the results of the food test (ii) Account for the results in c (i) above