A mechanism by which cancer cells can evade an immune response involves an alteration in the amount of MIC on the cell surface by _________. Group of answer choices cleavage of MIC at the cell surface by a protease decreasing the level of MIC transcription switching from a transmembrane form of MIC to a secreted form cytosolic degradation of MIC in proteasomes alternative mRNA splicing resulting in a truncated form of MIC that is no longer able to bind to NKG2D

Answers

Answer 1

Answer:

cleavage of MIC at the cell surface by a protease

Explanation:

The immune system refers to a complex network of cells and proteins that function to eliminate potentially tumorigenic cells on a daily basis. However, cancer cells show mechanisms in order to escape immune responses. MHC class I chain-related proteins A and B (MICA and MICB) are expressed in normal and tumorigenic cells where they act as ligands of the NKG2D receptor. The expression level of these proteins (MICA and MICB) is finely regulated by the activity of metalloproteinases (i.e., by protease-mediated cleavage), but this mechanism is altered in cancer cells. Recently, drug therapies that stimulate NKG2D mediated tumor destruction by reducing the cleavage of MICA and MICB from the surface of cancer cells have been developed.


Related Questions

Charlotte and her husband Frederick have genetic testing done. They both have a normal karyotype. The biggest difference between their karyotypes is _____.

Answers

chromosomes because it’s a man and women so the karyotypes will be different cause of their chromosomes or gender

An animal cell is dividing. Which of the following would not be seen during this process?
cleavage furrow
cytokinesis
cell plate
centrioles

Answers

Answer:

cell plate

Explanation:

9(5x + 1) ÷ 3y

From the expression above, provide an example of each of the following: sum, term, product, factor, quotient, and coefficient. If any are not present, write "not present."

Answers

Answer:

[tex] \frac{9(5x + 1)}{3y} \\ = \frac{3(5x + 1)}{y} \\ = \frac{15x + 3}{y} [/tex]

Answer:

               

Explanation:

replanting trees on a bare hillside is an example of
A) conservation and refforestation
B) preservation and conservation
C) restoration and preservation
D) refforestation and restoration ​

Answers

Answer:

A

Explanation:

firstly, conservation because by planting trees, the land dat was once proned to erosion is covered thereby conserving de land and reforestation because, u hv replaced trees dat were once cut there

The atomic number determines an elements identity and shows the number of _________________ in the atom.

A. protons + neutrons

B. nucleons

C. protons

D. neutrons

Answers

C

The atomic number is how many protons are in an atom’s nucleus

Answer:

c- protons??? I'm pretty sure

Plz help me I need help

Answers

water molecules are polar.

mark me brainliesttt :))

HELPPPP, ASAPPP THEY ONLY GAVE ME A FEW MINUTES TO COMPLETE!!

Discuss the benefits and drawbacks of
using solar energy and wind energy.

Answers

Answer:

hmm I'd say something like "Solar and Wind energy systems are renewable sources and ultimately are healthier for the planet, the drawback is that other resources (i.e oil and coal) tend to be cheaper"

Answer:

Solar Energy:-

Benefits-

Solar power is completely cleanIt produces no air pollution, no water pollution, no greenhouse gas effects and carbon - free alsoNo harmful emissions are released when electricity is being produced by solar panels.It also reduces the need for finite resources.

Drawbacks-

Solar Energy Storage Is ExpensiveUses a Lot of SpaceIts Weather-Dependent, slthough solar energy can still be collected during cloudy and rainy days, the efficiency of the solar system drops.Initial cost of purchasing a solar system is fairly high.

Wind Energy:-

Benefits-

Wind is a domestic source of energyIt's a clean fuel sourceIt's sustainable and causes no harmful emissions. Wind energy is a green energy source and does not cause pollution.

Drawbacks-

Wind turbines are prone to noise disturbances.The wind is inconsistentWind turbines involve high upfront capital investment.Installation can take up a significant portion of land.

The division of the nucleus is called
metaphase.
replication.
ОООО
cytokinesis.
mitosis.

Answers

It's mitosis:) mitosis is the process of nuclear division in eukaryotic cells That occurs when A parent cell divides and produces two identical daughter cells




5. Which statement is true of an organ system?
An organ system supports all parts of the
organism.
An organ system is not necessary for the survival
of the organism.
One organ system can take over for another organ
system
One organ system has no connection with other
organ systems.

Answers

organ system support all part of body

HELP PLS
Probability in Genetics (Drag each key word to its definition.)

Answers

Answer:

could u plz explane it berifly????

Explanation:

When someone says the word "desert," what plant do you picture? You're probably
picturing the saguaro cactus. Saguaros are known for their long, tall branches that look like
arms. These branches don't start to grow until the cactus is 50 to 70 years old. The folds
along the saguaro's stem and branches are called pleats. What are they for? These pleats
store water for the cactus, which is important in the hot, dry desert. A desert plant's spikes
aren't just to keep animals away. They also help provide shade during the long hours they
spend in the sun.
A saguaro cactus will
A
store water in its pleats.
B
shoot spikes at animals.
С
only live up to 70 years.
D
grow branches immediately

Answers

Answer:

It's A

Explanation:

please answer this for me

Answers

Answer:

The answer is a tape worm they are long and flat and can have more than one inside a animal, fish, human, and more

Los nombres de esos esos éteres y aldehidos

Answers

Explanation:

la respuesta está en la imagen de arriba

In the simulation, when protein molecules were evenly distributed on both sides of the membrane, was the solution isotonic, hypertonic, or hypotonic? Which direction was water flowing?

Answers

Answer:

1. Diffusion is the process of a substance moving from an area of high concentration to an area of lower concentration. Osmosis is a type of diffusion where water moves across a semipermeable membrane still from an area of high concentration of water to an area of lower concentration of water. This corresponds to water moving from an area with a low concentration of solute to an area with a higher concentration of solute.

2.

a. A semipermeable membrane allows some substances to pass through it.

b. The plasma membrane of a cell allows small uncharged molecules to pass through it, but not large molecules and not charged ions.

3.

a. The protein molecules were evenly distributed on both sides of the membrane, so this solution was isotonic.

b. In an isotonic solution, water moves both in and out of the cell, which was observed in the simulation.

4.

a. The protein molecules were more highly concentrated on the inside of the cell, so this solution was hypotonic.

b. In hypotonic solutions, water moves into the cell to help dissolve the higher amount of solute inside the cell, which was observed in the simulation.

5.

a. A semipermeable cell membrane is important to allow some molecules, like proteins, to be more highly concentrated inside the cell than outside the cell. If the cell membrane were permeable, the molecules on the inside of the cell would exit the cell and be evenly distributed in the cell and in its environment.

b. If the cell membrane were not permeable at all, the cell would not be able to receive nutrients from its environment.

Explanation:

When protein molecules were evenly distributed on both sides of the membrane, the solution is isotonic.

In isotonic solution the concentration of  solutes on side remain same .There is no net gain or less of water in isotonic solution.

What will be the direction of water flow in isotonic solution?The water will flow freely  across the cell membrane without any change in the concentration of solutes.In isotonic solution the cell neither shrink nor swell because the water concentration will remain same.

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do you think there is an aesthetic value that could be attached to the hides of the nguni cattle after slaughtering ?​

Answers

Answer:

The correct answer is - yes, these hides are used as aesthetic value.

Explanation:

Nguni hides are the secondary products after slaughtering the Nguni cattle farmed in South Africa. These skins or hides are used to make many aesthetic values and beauty items such as floor rugs. These hides are not only famous for their natural beauty but also due to their incredibly hard-wearing and very easy to clean.

Other than Floor rugs these are also used as furniture in rich houses and lodges. These hides are used to make shoes, leather jackets, car leather, and many more.

If a person is operating a leaf blower at 110 decibels, and using a pair of noise cancelling headphones that reduces the relative intensity by 100 times, will the sound be in the safe range of human hearing?

Answers

Answer:

Yes

Explanation:

Summarize the functions of the vertebral column

Answers

Answer:

function of vertebral column

Explanation:

The major function of a vertebral column is to protext the spinal cord,it also provides stiffening for the body and attachment for the pectoral and pelvic girdle and many muscles. In human an additional function is to transmit body weight in walking and standing.

Why did Gregor Mendel choose to use purebred plants in his experiments?
A They reproduce sexually.
B They exhibit only one form of a trait.
C They have a variety of traits.
D They reproduce asexually.

Answers

Answer:

B

Explanation:

Gregor Mendel chooses to use purebred plants in his experiments because they exhibit only one form of a trait. The correct option is B.

What is Mendel's experiment?

Mendel altered pure pea plant lineages. First-generation hybrids (F1) displayed dominant qualities like purple flower color while hiding recessive traits like white bloom color.

But in second-generation (F2) pea plants, recessive characteristics returned in a 3:1 ratio (dominant to recessive). Every pea plant has both male and female reproductive organs, and they all typically procreate by self-pollinating.

This was crucial to make sure that there were no other factors influencing the result of the cross when he crossed two plants with different features.

Therefore, the correct option is B, They exhibit only one form of a trait.

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Which of the following statements about the nucleus is NOT true?

A. The nucleus contains DNA proteins that make RNA copies of DNA.
B. The nucleus is the site of protein assembly.
C. The nucleus stores the coding instructions for constructing the cell's proteins.
D. The nucleus is surrounded by a membrane that lets materials in and out.

Answers

Answer:

statement A is not true.

Which animal adaptation happened before the others?

A. Reproduction on land

B. Lungs

C. Backbone and skull

D. Development of a coelom

Answer: D. development of a coelom ​

Answers

Answer:

D?

Explanation:

What are valence electrons?
A. the atomic mass

B. the atomic number

C. all of the electrons in an atom

D. electrons in the outermost energy level

Answers

Answer:

D

Explanation:

The simple answer is the electrons in the outermost energy level.

Hydrogen has 1 electron in the outermost energy level.

Magnesium has 2 so this tells you that magnesium has a charge of 2

Oxygen has 6  oxygen has a charge of - 2

Fluorine has 7

For most elements, the electrons in the most outer ring determine the valence of the element.

Notice that the non metals work differently than the metals. Mg may have a charge of 2 and that is the number of electrons in the valence right.

Oxygen is a non metal it has a charge of - 2. It gets 6 electrons by subtracting the number of its charge from 8.

Answer:

D. electrons in the outermost energy level

Explanation:

The valence electrons are the electrons in the outermost energy level.

Which is the best way to describe the biodiversity of an area?

Answers

Answer:

The best way to describe of biodiversity in a area is a grassland with a wide variety of organisms living on it.

Explanation:

A person who forwards on a sexual picture of another can get in as much trouble as a person sending a picture of themselves (sexting).


True
False

Answers

the answer to this is true

The statement about the s exual pictures is TRUE.

The person might get convicted for the crime and can severely punished if he post or share the pictures without consent.It comes under cyber crime.

What come under cybercrime?Child P ornography OR Child s exually abusive material (CSAM) Cyber Bullying. Cyber Stalking. Cyber Grooming. Online Job Fraud. Online S extortion. Phishing. Vishing

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Energy
as it transfers from one consumer to the next.
increases
decreases
stays the same

Answers

Explanation:

increases

I hope I helped u >~<

How many amino acids must be obtained in the diet because they cannot be made by the body? A. 2 B.5 C.10 D.20

Answers

Answer: C

Explanation: Just is.

What would happen if glycolysis could not happen in a cell?
O A. The cell would use anaerobic respiration.
O B. The cell would not produce ATP molecules.
O C. The cell would produce more energy.
D. The cell would begin fermentation.

Answers

Answer:

B. The cell would not produce ATP molecules.

Cuanta poblacion tiene Yunga?

Answers

Tiene 1570 poblacion yunga

Answer:

1570

Explanation:

which of the following shapes is not a common shape of a prokaryote?
a. bacilli
b. cocci
c. cylinder
d. spirochetes

NO WRONG ANSWERS PLS

Answers

Answer:

c

Explanation:

A scientist separates a population of lizards into two groups. What would
most likely increase the rate of speciation in this population?
A. Have one group breed twice as often as the other.
B. Keep the two groups apart, but in identical ecosystems.
C. Force the two groups to breed with each other.
D. Have one group live with a much stronger predator.

Answers

Answer:

Hi, there your answer is D. Have one group live with a much stronger predator.

Explanation:

Having one group live with a much stronger predator will most likely increase the chances of speciation.

What is speciation?It is a process by which a new species of an organism is created.It occurs due to evolution.It occurs when a portion of population gets separated from the original population and evolves different characters that are heritable.Will speciation occur if :one group breeds twice as often as the other? No, because no selective force is acting on it.both groups are in identical ecosystem? No, since no reason for adapting and evolving a new character will be there.both groups interbreed? No, there is no competition, no struggle for existence and hence no evolution occurs.one group lives with a strong predator? Yes, since they will evolve evasive mechanisms and characters.

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How are many unicelled organisms. In addition , anything less than a cell is not alive. What do these statements imply about cells?

Answers

Answer:

The correct answer is - cells are the basic unit of life.

Explanation:

As it is given and also known that there are many unicellular organisms exists and they do not require the multicellular body to live their life or survival. Multicellular organisms are made up of various cells joined together to form a complex organization.

Anything less than a cell can not live or survive and also do not called a living entity. So, from above we can say the basic unit of the life is cell.

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