Action Potential: Relative refractory period
In a neuron, there is a period of time called the absolute refractory period where it is impossible for an action potential to
begin. This corresponds to the change in membrane potential from +30 to -70 mV, or the repolarization phase. Towards the
end of the repolarizing phase, there is a relative refractory period where it is difficult, but not impossible, for another action
potential to begin. Using the time slider function, which of the following segments in the neuron would correspond to a
relative refractory period?

A second action potential can be triggered during the relative refractory phase, but it will need a stronger stimulus to do so than the first time. Refractory times are brought on by the inactivation gate of the Na+ channel.

The axon has a tougher time producing successive action potentials during this time period, which is referred to as the refractory period, as a result of these transient alterations.

As a result, the refractory period restricts the quantity of action potentials that a certain nerve cell can generate in a given amount of action potentials time.

If enough powerful stimuli are applied to the neuron after the absolute refractory time, Na+ channels start to recover from inactivation and the neuron may respond once again by generating action potentials.

Therefore, A stimulus that is stronger than usual is required to generate neuronal activation during the relative refractory period.

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