As the most junior member of a lab, you are tasked with generating cell lines that accumulate DNA damage to investigate how random mutations affect transformation of cells into cancer cells. You decide to mutate proteins in the p53 pathway. Which three proteins would you mutate

Answer:

In p53 pathways, 3 proteins which are mutate and cause cancer that proteins are:

1.BRCA2  

2. p53 in Rb genes binds with deoxyribonucleic acid that stimulates another gene to produce a protein known as p21 that interacts with cdk2. When p21 is combined with cdk2  cell will not pass through to the next stage of cell division. This is Li-Fraumeni syndrome (when p53 causes cancer from parents to offspring)  

3.BRCA1  

The parent that transmits mutation in one of these genes has a 50% chance of inheriting the mutation. The effects of mutations in BRCA2 and BRCA1 are seen when the person's second copy of the gene is normal.

Which of the following statements best explains the hypothesis that the development of sexual reproduction has resulted in acceleration of the rate of evolution?
(A) Mutations are more likely to occur in spermatogenesis and oogenesis than in mitotically dividing cells.
(B) Sexual reproduction results in more offspring than does asexual reproduction.
(C) Those members of a species that are best adapted to their environment are most likely to be successful in sexual reproduction.
(D) Mutations usually do not occur in the production of spores or in cells dividing by fission.
(E) Sexual reproduction is more likely to result in genetic recombination than is asexual reproduction.

A family is relocating from St. Louis, Missouri, to California. Due to an increasing inventory of houses in St. Louis, it is taking longer than before to sell a house. The wife is concerned and wants to know when it is optimal to put their house on the market. Her realtor friend informs them that the last 21 houses that sold in their neighborhood took an average time of 60 days to sell. The realtor also tells them that based on her prior experience, the population standard deviation is 14 days.
What assumption regarding the population is necessary for making an interval estimate for the population mean?

Why does sexual reproduction increase the genetic variation in a species

The nervous system interacts with the endocrine system by ____.

A. sending neurotransmitters to endocrine target cells

B. sending neurotransmitters to neuroendocrine cells

C. translating messages from endocrine cells

D. receiving messages from hormones

Fat cells are expandable. How does this structure relate to a fat cell's function?

A) Fat cells store energy for the body to use later, so being
expandable would help with storage.

B) Fat cells burn energy quickly when other food source is available, so being expandable would help with the rapid burn.

C) Fall cells protect organs, so being expandable can help with cushioning.

D) Fat cells do not expand

Which nutrient, identified in the 2010 Dietary Guidelines for Americans, is considered "a nutrient of concern"?

explain the factors that contribute to the success of class insecta. ​

define the term colony as it relates to bacterial growth on solid media

Making Inferences Why do
you feel pain when you pull on
your hair or nails, but not when
you cut them?

ecologically, termites are classified as a carnivore b, detritivores c, insectivore d, herbivore

pa help naman po....

witch element are involved in creating genetic matirials

which of the following hypotheses can be tested with experiments? select all that apply

1.) a diet low in sugar reduces the risk for heart disease
2.) coffee increases subject performance on intelligence tests
3.) people that brush their teeth live longer than those who don't brush their teeth
4.) scientists will find a cure for cancer before the year 2020

I know that 4 isn't the answer so I selected the other three and it said I was wrong. isn't a hypotheses something that can be experimented on so can't all of the three have experiments If I'm making sense ​

Describe a solution that provides freshwater by accessing it as it exists in nature. pls help

The table below shows the use of some energy production methods over time.


Type of energy Average energy used annually in the past (in million tons) Average energy used annually at present (in million tons) Average energy most likely to be used annually in the future (in million tons)
Oil 200 4000 300
Gas 100 2500 700
Coal 1000 2500 1500
Wind 0.1 50 2000
Hydropower 0.7 60 150
Tidal power 0.02 50 500

Based on the table, which of these statements best describes the impact of different methods of energy production on the environment in present times?
Wind energy may be altering all shorelines on Earth.

Hydropower may be altering all shorelines on Earth.

Tidal power may not be contributing significantly to climate change.

Coal energy may not be contributing significantly to climate change.(Not this)

Dichotomous key (PLZ HELPLPP)

describe how a jump rope could be used to model the cell membrane of a plant cell

Which feature of the ocean floor is caused by one tectonic plate moving under another at a convergent boundary? A. A flat plain B. A mid-ocean ridge C. A continental shell D. A trench PREVIOUS​

A scientist is studying the impact of a new manufacturing plant on the local ocean ecosystem. How could she best monitor the impact of the manufacturing plant on populations in this ecosystem? A. She could perform several wildlife surveys over time to observe any changes in the number and type of marine organisms in the ecosystem. B. She could add a chemical to the water to react with the waste products that the manufacturing plant is dumping into the marine ecosystem. C. She could ask the manufacturing plant to treat all of the waste products that they are dumping into the marine ecosystem. D. She could collect data on the amount of product made by the manufacturing plant and how much the product sells for in local cities.

what is it called when a seismic wave bends as it passed from liquid to solid

what defies a species?

Which of the following is a base used in DNA replication that is NOT used in translation?


i need asap!
​

Which of these is true for a fertilized egg?
O A. It has DNA from both parents.
B. It has a haploid number of chromosomes.
O C. It has DNA but no chromosomes.
.
D. It has too many chromosomes until it splits.

Which diagram correctly shows how h-zygous alleles are found on h-logous chromosomes?

how are seasons in the northern hemisphere related to seasons in the southern hemisphere?

Questions
A macaw is a type of parrot with colorful feathers that flies about in the upper canopy of trees in tropical rainforests. Macaws have a diet which includes
fruits, leaves, nuts, and seeds of plants. Which of the following describes a biotic factor of the macaw's habitat that provides a survival advantage for
these birds?
o
The colorful feathers are lost and regrow each year
0
Some rainforest predators are able to climb trees
o
Trees provide shelter and a macaw

- How do acidic and alkaline environments affect the growth and survival of bacterial?

HELP!!!!!
I WILL MARK YOU AS THE BRAINLIEST ANSWER!!!

Annotate the symbol by the reference image. Then, explain why this symbol represents an ion and how many electrons it has.

• the name of the element
• the charge
• the mass number
• the atomic number

What would most likely happen to a unicellular if it was exposed to a hypotonic solution for an extended period of time

how can an irreverible step in a metabolic pathway be reversed?


A. When both the reactants and products have equal amounts of energy


B. When the reactants contain large amounts of energy


C. When another chemical reaction with a large amount of energy occurs at same time


D. when collision of substances generate the energy needed




how can an irreverible step in a metabolic pathway be reversed?


A. When both the reactants and products have equal amounts of energy


B. When the reactants contain large amounts of energy


C. When another chemical reaction with a large amount of energy occurs at same time


D. when collision of substances generate the energy needed




Order the sequence of events in transcription?


1- free ribonuleotide triphosphates base-pair with the deoxyribonucleotides in the DNA template


2- RNA polymerase binds to the promoter region of a gene


3- primary rna transcript is formed


4- two DNA strands are seperated




Which organic molecule is not found on the plasma membrane?


A. carbohydrates


B. cholestrol


c. phospholipids


d. proteins




What does this statement mean : "Information flow between cells tissues and organs is an essential feature of homeostasis and allows for integration of physiological processes"




A. the nervous system is the most prominent body system for integration of physilogical processes


B. some substances can affect local processes while others travel to exert their effects on other distant parts of the body


C. communication between body structures through body fluids is the most important physiological processes


D. Neurotransmitters, hormones, paracrine and autocrine substances exert their efferts locally as well as distant body structures




which statement best describes the orientation the phospholipid molecules in a membrane:


A.) the nonpolar fatty acids are oriented towards the cholestrol molecules


B.) the hydrophilic layer is oriented towards the middle of the phosphlipids


C.) phospholipids align themselves in the membrane in a bimolecular layer


D.) the hydrophobic and hydrophilic structures point away from the cell




Which is NOT a product of glycolysis under aerobic and anaerobic conditions?


A.) lactate


B.) FADH


C.) pyruvate


D.) NADH




Which reason is why water is an essential nutrient?


A.) water needs to move between compartments


B.)can be obtained through ingestion


C.) body cant make enough water for its needs


D.) water evaporates from the skin that has the largest surface area among all body structures