In arthritis, there is deposition of urate crystals in joints. If you want to treat the arthritis by decreasing the concentration of circulating uric acid, what will you do with its mechanism in kidney?

Answers

Answer 1

Answer and explanation:

If I'd wanted to decrease the concentration of circulating uric acid by altering its mechanism in the kidney, I would administer a drug that would inhibit uric acid reabsorption and increase its excretion through urine.

Arthritis is a condition characterized by inflammation of the joints and can be caused by many diseases. When the cause of this arthritis is the deposition of urate crystals in the joint because of an increase in the concentration of circulating uric acid (hyperuricemia) we are most likely talking about gout, a painful disease that can deform the joints.

Hyperuricemia and gout have many risk factors associated with them, such as genetic predisposition, unhealthy diet, and suffering from other conditions like Diabetes.

Several medications are used in the treatment of the symptoms and the prevention of the worsening of this disease, but the one that is most frequently used to increase the excretion of uric acid is Probenecid. Probenecid blocks the kidney's OAT (organic anion transporter) that reabsorbs uric acid in the kidney tubules, thus enhancing its excretion and decreasing uric acid's blood concentration.


Related Questions

What is a disadvantage of using a space-filling model to show a chemical compound?

Answers

Answer:

Explanation:

The appropriate answer is 'space filling models do not identify the number and type of bonds'. A space filling model is one type of three dimensional (3D) molecular model used to represent molecules of different chemical compounds. The structure of this type of arrangement shows that, for example, two elements are bonded but it does not show if it is a single, double or triple bond.

1 Reproduction is an important characteristic of living organisms.Explain

Answers

Answer:

Reproduction is one of the most important characteristics of living beings, because -

- The existence of any species is dependent on the reproduction because no living being is immortal.

After death of a being of one generation,the existence of that died being is completed by the newborns of the next generation.

And,the birth of newborns of next generation is only possible by the reproduction.

- The variation and mutation in the biological characteristics is often necessary which is only possible by reproduction through many generations.

- When a living being becomes old, it's become unable to do normal tasks like collection of food, finding shelter etc,at that moment,the newborns of next generation do the necessary jobs.

And as mentioned before,these newborns are only possible due to reproduction.

How do the frequencies of the waves compare?

Wave A has a higher frequency because it has a larger amplitude.
Wave A has a lower frequency because it has a longer wavelength.
The waves have the same frequency because they have the same wavelength.
The waves have the same frequency because they have the same amplitude.

Answers

Answer:

The waves have the same frequency because they have the same amplitude.

Neurons are best described as:

Answers

Answer:

neutral?

Explanation:

What do you mean by photosynthesis?


bore D D D D ​

Answers

Answer:

photosynthesis is the process in which plant make food by themselves from using sunlight, water, and carbon dioxide to create oxygen and energy in the form of sugar.

Answer:

Photosynthesis is a process through which plants and other organisms transform light energy into chemical energy, which is then released to power the organism's metabolic processes through cellular respiration.

OAmalOHopeO :)

During respiration, carbon dioxide diffuses from the blood across the alveolus and into the lungs. Which factor increases the diffusion rate of carbon dioxide?

Answers

Explanation:

There are some factors which affect the rate of diffusion. These are:-

The partial pressure of oxygen.

The partial pressure of carbon dioxide.

Temperature.

The concentration of gases.

The thickness of the membrane.

hope this helps you

have a nice day :)

Answer:

the thickness of membrane

Within the Phylum Mollusca, what is the
radula?
A. the organ that grinds up food before digestion
B. the organ that turns into the shell of the animals
C. the organ that circulates blood through the organism

Answers

Answer:

I think the ans is no.a ok

please mark as brainliest

the drug which is used to reduce pain is ..,....

i) opium ii) bhang iii) hashish iv) marijauna​

Answers

Answer:

hashish

Explanation:

opinum

Explanation:

because it is used to make pain nubbing/pain killer

List three of water’s unique properties.

Answers

Explanation:

1.water is called universal solvent it can dissolve almost every solute on it

2.water can show anamolus expansion which mean it density will me most on 4 degree celsius

3.it is neutral substance

universal solvent, water cane expand, neutral substance

What is the process in genetic expression?

Answers

Answer:

Explanation:

Gene expression is the process by which the instructions in our DNA are converted into a functional product, such as a protein. It acts as both an on/off switch to control when proteins are made and also a volume control that increases or decreases the amount of proteins made.

Identify the incorrect statement regarding the fundamental causes of edema. Multiple Choice Capillary reabsorption does not depend on oncotic pressure. A deficiency of albumin (hypoproteinemia) produces edema by reducing the reabsorption of tissue fluid. Kidney failure leads to water retention and hypertension, thus raising capillary blood pressure and filtration rate. Obstruction of lymphatic vessels can interfere with fluid drainage and lead to the accumulation of tissue fluid distal to the obstruction. Since albumin is produced by the liver, liver diseases, such as cirrhosis, tend to lead to hypoproteinemia and edema.

Answers

Answer:

Capillary reabsorption does not depend on oncotic pressure

Explanation:

Edema refers to the swelling caused by the fluids trapped in the body's tissues, which swell from injury and/or inflammation. Edema can be associated with the decrease in plasma oncotic pressure, i.e., osmotic pressure exerted by proteins (especially albumin) in the blood vessel's plasma, the increase in hydrostatic pressure, or the increase in the capillary permeability. Moreover, capillary reabsorption refers to the movement of fluid from interstitial space to the capillaries, which is driven by the blood colloidal osmotic pressure. Lymphatic obstruction, i.e., the blockage of the lymph vessels that drain fluids from tissues, may cause edema in the part that is drained by the affected vessels (it is known as lymphedema). Moreover, liver/kidney failure may lead to edema by decreasing albumin and oncotic pressure. When plasma albumin levels drop because of liver diseases, the colloid osmotic pressure also decreases. In consequence, liver diseases, including stage 3 cirrhosis, lead to the development of swelling in the abdomen, thereby leading to edema.

your body's internal feedback loops work by responding to???

A) information from the external environment

B) hormones from the pineal gland

C) changes in the internal environment

D) messages sent by the brain to body organs

Answers

Answer:

Option C

Explanation:

external structure of Amoeba​

Answers

Answer:

Structure of amoeba primarily encompasses 3 parts – the cytoplasm, plasma membrane and the nucleus. The cytoplasm can be differentiated into 2 layers – the outer ectoplasm and the inner endoplasm. The plasma membrane is a very thin, double-layered membrane composed of protein and lipid molecules.

Explanation:

Briefly explain what happens during Meosis 1.

Answers

Answer:

Explanation:

During meiosis one cell, divides twice to form four daughter cells. These four daughter cells only have half the number of chromosomes of the parent cell.  they are haploid. Meiosis produces our sex cells or gametes. (eggs in females and sperm in males)

Chemosynthesis _______. Question 11 options: uses energy derived from hydrocarbons and hydrogen sulfide in place of solar energy produces carbohydrates and sugars occurs around hydrothermal vents near the oceanic ridge system Both a and c are correct. All of the above are correct.

Answers

Answer:

The answer is all of the above are correct.

Explanation:

Chemosynthesis occurs in bacteria and other organisms and involves the use of energy released by inorganic chemical reactions to produce food. All chemosynthetic organisms use energy released by chemical reactions to make a sugar, but different species use different pathways. For example, at hydrothermal vents, bacteria oxidize hydrogen sulfide and add carbon dioxide and oxygen to produce sugar, sulfur, and water:  

CO2 + 4H2S + O2 ⇒ CH20 + 4S + 3H2O.

Chemosynthesis is the process by which food (glucose) is made by bacteria using chemicals as the energy source, rather than sunlight. Chemosynthesis occurs around hydrothermal vents and methane seeps in the deep sea where sunlight is absent. During chemosynthesis, bacteria living on the seafloor or within animals use energy stored in the chemical bonds of hydrogen sulfide and methane to make glucose from water and carbon dioxide (dissolved in seawater). Pure sulfur and sulfur compounds are produced as by-products.

Complete the table by filling in the missing information. Use these choices:

frameshift
substitution


7. UGU-CCG-GAA-CGA

UGC-CGG-GAA-CGA

8. GAA-CGU-AGC-GGU

GAU-CGU-AGC-GGU

9. UGU-UUC-CCU-UAA

UGU-UCC-CUU-AA

Answers

Answer:

7. Substitution mutation

8. Substitution mutation

9. Frameshift mutation

Explanation:

A substitution mutation is any kind of mutation that involves replacement of one or more nucleotide base by another in a sequence.

A frameshift mutation, on the other hand, is a mutation that changes the reading frame of the sequence. Two types of mutations cause frameshift viz: insertion and deletion mutation.

In the following sequences, mutation has occured as follows:

7. UGU-CCG-GAA-CGA to UGC-CGG-GAA-CGA - Substitution mutation has occured because nucleotides C and G has replaced C and U in the first and second codons respectively.

8. GAA-CGU-AGC-GGU to GAU-CGU-AGC-GGU- A substitution mutation because nucleotide U has replaced A in the first codon.

9. UGU-UUC-CCU-UAA to UGU-UCC-CUU-AA - A frameshift mutation because nucleotide U has been removed from the second codon, hence, causing a change in the reading frame.

What cycle of replication is used by the common cold virus?
A: Dormant cycle
B: Replication cycle
C: Lytic cycle
D: Lysogenic cycle

Answers

Answer:

C

Explanation:

The lytic cycle involves the reproduction of viruses using a host cell to manufacture more viruses; the viruses then burst out of the cell. The lysogenic cycle involves the incorporation of the viral genome into the host cell genome, infecting it from within.

The common cold virus is replicated using the lytic cycle, by introducing its genome into the host and using its cellular machinery, hence option c is correct.

How common cold virus replicate?

The common cold virus is replicated by using the lytic cycle, in which the virus introduces its genome into the host genome and uses all the replicating machinery of the virus.

The lysogenic cycle is different from the lytic cycle in which the viral genome replicates on its own and does not integrate its genome into the host genome.

After replicating its genome with the host genome, the viral genome is excised from the host genome and assembled into new viral particles for infecting other host cells. The new viral particle lysed the host cell and spread to other cells.

Therefore lytic cycle is used by the common cold virus, hence option c is correct.

Learn more about replication in common cold virus, here:

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Which of the following is a heterotroph?
*cyanobacteria
*gopher
*fir tree
*dandelion

Answers

Correct Answer is gopher

Select the correct answer.
Why do plants excrete more carbon dioxide at night than during the day?
A.
Cellular respiration occurs only at night and not during the day.
B.
Cellular respiration occurs at a faster rate at night than during the day.
C.
Photosynthesis uses some of the carbon dioxide released during the day.
D.
The light-independent reaction of photosynthesis that releases carbon dioxide occurs at night.

Answers

Answer:

D

Explanation:

because they cannot do photosynthesis at night.

Answer:

The answer is C. Photosynthesis uses some of the carbon dioxide released during the day.

Explanation:

Which of the following diseases is not caused by viruses?

Measles
Chickenpox
AIDS
Malaria

Answers

Answer:

malaria isn't caused by bacteria

Which of these is an example of an adaptive )or specific) immune response

Answers

Adaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system's ability to target specific pathogens, and memory refers to its ability to quickly respond to pathogens to which it has previously been exposed.
___IgD: B. This class of antibody is the first to appear after activation of B cells
___IgM: E. This class of antibody is not secreted by B cells but is expressed on the s...
___IgE: C. This class of antibody is involved in the defense against parasitic infections ...
___IgA: A. This class of antibody is the only one that can cross the placenta

What questions do you have about skin and skin color?

Answers

Answer:

nothing I have☺️☺️☺️☺️☺️☺️☺️☺️☺️

How do I make a Punnet Square without knowing if traits are Dominant or Recessive? I cannot refer to the parents of the current generation, so I have to rely on that generation to create a theoretical next generation.

Answers

If you are referring to a previous generation, that would probably mean that the traits they have are the dominant ones

Explanation:

if you know all the traits possible, then the ones the parents have of a previous generation are most likely the dominant ones, from there, you can hopefully figure out another generation. could you attach a picture if this didn't help? thanks

In this assignment, you will expand your knowledge of muscle structure and function by exploring muscle strength and contraction. Then, you will use what you learn to answer some follow-up questions.

Read the article and use the information to answer the following questions.

Strongest Muscle

Name the four ways muscle strength can be measured and briefly describe each.

Answers

Answer:

Absolute strength measures maximum force.

Dynamic strength measures repeated motions.

Elastic strength measures exertion of force rapidly.

Strength endurance measures fatigue resistance.

Explanation:

im megaminds child

Absolute strength measures maximum force. Dynamic strength measures repeated motions. Elastic strength measures exertion of force rapidly. and Strength endurance measures fatigue resistance.

What is Muscle strength ?

Physical strength and muscular endurance share some characteristics, they also differ significantly. Your ability to apply force or lift weights is a measure of your muscular strength. Using heavier weights for fewer repetitions helps develop muscular strength.

The term "muscular endurance" describes a muscle's capacity to endure prolonged periods of repeated contractions against opposition.

Long-distance running, cycling, or swimming, as well as bodyweight exercises and circuit training, are exercises that increase muscle endurance.

To learn more about Muscle, refer to the link:

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What process facilitates locomotion for the ovum?

Question 6 options:

a. Once the ovum leaves the ruptured follicle it is captured by the uterus and then directed into the Fallopian tube, where it is pushed along towards the oviducts.


b. Once the ovum leaves the ruptured follicle it is captured by the fimbriae and then directed into the Fallopian tube, where it is pushed along towards the uterus via cilia.


c. Once the ovum leaves the ruptured follicle it is fully matured and propels itself into the Fallopian tube, where it moves along towards the uterus.


d. Once the ovum leaves the ruptured follicle it is captured by the cervix and then directed into the Fallopian tube, where it is pushed along towards the uterus via cilia.

Answers

The correct answer is B. Once the ovum leaves the ruptured follicle it is captured by the fimbriae and then directed into the Fallopian tube, where it is pushed along towards the uterus via cilia.  

Explanation  

Ovulation is a process that occurs during the menstrual cycle that occurs around day 14 of the cycle. In the ovulation process, the eggs go through different places before reaching the uterus (their final destination). The first step is when the egg leaves the broken follicles. The second step is when it is taken to the fallopian tubes (place where fertilization occurs) through the fimbriae. The third step is when the egg uses the cilia to reach the uterus.

Describe hydrophobic interactions, the conditions under which they occur, and the probable influence they have on protein structure. Group of answer choices These are nonpolar side chains of amino acids that tend to associate to form hydrophobic clusters usually away from the protein surface. These are nonpolar side chains of amino acids that tend to destroy hydrophobic clusters away from the protein surface. These are polar side chains of amino acids that tend to associate to form hydrophobic clusters usually close to the protein surface. These are polar side chains of amino acids that tend to destroy hydrophobic clusters close to the protein surface.

Answers

Answer:

Nonpolar side chains of amino acids tend to associate to form hydrophobic clusters usually away from the protein surface.

Explanation:

Hydrophobic interactions are defined as the relationship between the low water soluble molecules named hydrophobes and water. They contains a long chain of carbon atoms and are usually considered as a nonpolar molecules.

They occur when the non polar amino acids are associated to produce the hydrophobic clusters that are usually away from the surface of the protein.

Explica como crees que se originó la vida sobre el planeta tierra

Answers

Sabemos que la vida comenzó hace al menos 3.500 millones de años, porque esa es la edad de las rocas más antiguas con evidencia fósil de vida en la tierra. Estas rocas son raras porque los procesos geológicos posteriores han remodelado la superficie de nuestro planeta, a menudo destruyendo rocas más viejas y creando otras nuevas (lo siento si es un amor incorrecto, marque como más inteligente si es correcto).
La pregunta del cómo empezó la vida en la Tierra es una de las más difíciles (e interesantes) que se pueden plantear. De hecho, el origen de los seres vivos encierra varias cuestiones clave: ¿cuándo ocurrió?, ¿pudo producirse más de una vez?, ¿cómo fue la transición entre la química y la biología?, ¿tuvo lugar en la Tierra o fuera de ella? Y, a medio camino entre la ciencia y la filosofía: ¿fue fruto del azar o de la necesidad?

La investigación experimental sobre el origen de la vida comenzó en la década de 1950, con el trabajo de dos científicos pioneros en una disciplina llamada química prebiótica: Stanley L. Miller y Joan Oró. Las pruebas acumuladas desde entonces nos indican que la vida probablemente comenzó hace unos 3.800 millones de años, sólo 700 millones de años después de la formación de nuestro planeta. En el gran laboratorio de química que era la Tierra primitiva se sintetizaron las primeras moléculas orgánicas, que fueron organizándose progresivamente para formar otras más largas y complejas.

If the gene sequence of DNA is A T T C G A C T C G what will the complementary mRNA sequence be that is made during transcription?

Answers

Answer:

U A A G C U G A G C

Explanation:

The complementary bases in RNA are the same as DNA with G-C (guanine to cytosine).

But, they are different in that RNA has A-U (adenine to uracil) instead of A-T (adenine to thymine).

Using these RNA base pairs of G-C and A-U, create the complementary mRNA sequence:

A T T C G A C T C G

Translate:

U A A G C U G A G C

So, the complementary mRNA sequence will be U A A G C U G A G C

.Origin of species was given by

Answers

Answer:

Charles Darwin

Explanation:

They were given by Charles Darwin

The graph shows the history of human population growth

Answers

Answer:

exponential growth, c.

Exponential growth is iconic for ramping up, resulting in a near vertical line by the time its really going.

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Assume that transportation costs are especially high for Widgets in the two-country, two-product Ricardian model, and Country A enjoys a comparative advantage in Widgets, then A) country B must also enjoy a comparative advantage in Widgets. B) country B may end up exporting Widgets. C) country A may switch to having a comparative advantage in the other good. D) country A will still export Widgets. E) trade may be impossible between the two countries. PLZ HELP ME I NEED TO GET THIS RIGHT 20 POINTS1.) the table shows the weight in kilograms of 10 players on a college basketball team.Weight (kg)[54, 52, 65, 63, 62, 60, 58, 53, 51, 50]Which statement is NOT true about this data?A.) the median is one of the values listed in the tableB.) the mode of the data is 60C.) the mean is less than the medianD.) the data set had no matter2.) This table shows the amount of money in dollars that a group of seventh grade students spend on food each day.Carol=2Anna=3Sophie=11Tom=3Jackie=1Which measure of central tendency is most affected by the amount of money that Sophie spends?A.) the median onlyB.) the mean onlyC.) the mode onlyD.) the mean and the median3.) This table shows the results of a survey that asked a group of people what time of day their favorite tv show aired.5:00=36:00=57:00=108:00=219:00=2510:00=1511:00=12What time corresponds to the mode of this set of data?A.) 8:00 pmB.) 9:00 pmC.) 10:00 pmD.) 11:00 pm Open the sash half way up, take the beaker containing the dry ice / water out of the hood, and slowly move it from right in front of the hood all the way down to the floor. At what point do the fumes stop getting sucked up by the fume hood? A block of amber is placed in water and a laser beam travels from the water through the amber. The angle of incidence is 35 degrees while the angle of refraction is 24 degrees. What is the index of refraction of amber?(index of refraction of water is 1.33) What are the x-intercepts for the function (x) = -x(x 4)? A 0 B -1, 4 C 4 D 0, 4What are the solutions to the quadratic equation 4x2 x 3 = 0? Bit op-amp c Vsat = 12V, R1=R2=R3=R4=R, dng sng in p Vi(t) c cho nh hnh 2.16b a. Tnh V0 theo Vi, li p AVb. V li dng sng in p V0(t) khi Vm= 38 V c. V li dng sng in p V0(t) khi Vm = 5V Rearrange the Jumbled sentences:The Dog Went With Them.pls rearrange the jumbled sentences for this question guys.HELP MEPLS A 10-ft ladder, whose base is sitting on level ground, is leaning at an angle against a vertical wall when its base starts to slide away from the vertical wall. When the base of the ladder is 6 ft away from the bottom of the vertical wall, the base is sliding away at a rate of 4 ft/sec. At what rate is the vertical distance from the top of the ladder to the ground changing at this moment? Which of the following graphs represents a one-to-one function? On a coordinate plane, a function has two curves connected to a straight line. The first curve has a maximum of (negative 6, 4) and a minimum of (negative 4.5, negative 1). The second curve has a maximum of (negative 3.5, 2) and a minimum of (negative 2.5, 0.5). The straight line has a positive slope and starts at (negative 2, 1) and goes through (1, 2). On a coordinate plane, a circle intersects the x=axis at (negative 2, 0) and (2, 0) and intercepts the y-axis at (0, 4) and (0, negative 4). On a coordinate plane, a v-shaped graph is facing up. The vertex is at (0,0) and the function goes through (negative 4, 4) and (4, 4). A coordinate plane has 7 points. The points are (negative 4, 1), (negative 3, 4), (negative 1, 3), (1, negative 3), (3, negative 4), (4, negative 2), (5, 3). Mark this and return Value of [(3/2)^(-2)] is* I need help asap!!!!Please explain the answer A new employee, John Chapman, earns $10 per hour and gets time-and-a-half over 40 hours per week. His first week he worked 45 hours. Deductions from his check were $30 for OASDI, $7 for Medicare, $ 61 for federal income tax withholding, and $15 for a United Way contribution. What was his gross pay for the period 385 x 42.13 x 0.079 is (consider significant figures): Which of the following rational functions is graphed below?oA. F(x) = 1/2xB. AX) = 1/x-2C. F(x) = 1/x+2 Find the center and radius of the circle and sketch its graphX^2+y^2=9 substitute for A,P and T in the fomula A=P (1+r)^t,give that A=1 000 000,P=10 000 and T=2,and express as a quadratic equation Select the correct answer.Which statement is true of Web-based social media?A. They allow consumers to interact with and update content.B. They cannot be updated easily, as compared to print media.C. They are expensive to produce and maintain, as compared to print and television.D. They can exist independent of the Internet. At what respect can the present constitution of Nepal be considered superior? write in 7 points the mode of 3,5,1,2,4,6,0,2,2,3 is giving out brainliest How can visual images create feelings of unease and fear?