Many of the phenotypes of DiGeorge syndrome have been traced back to one of the genes that is in the deleted region, TBX1. Some of the evidence for the important role of TBX1 in DiGeorge syndrome came from individuals who have some of the symptoms of DiGeorge syndrome without having the typical deletion. Closer examination showed that some of these individuals had SNV in the TBX1 gene. Which of the following SNVS would be most likely to create a similar phenotype to the deletion?
A. A variant in the promoter region of TBX1 that increases its expression
B. A variant in the intronic region of TBX1 that does not affect splicing. X
C. A nonsense variant near the 5' end of the TBX1 gene.
D. A silent variant near the 5' end of the TBX1 gene.

Answers

Answer 1

Answer:

D. A silent variant near the 5' end of the TBX1 gene.

Explanation:

TBX1 gene is wild type human being. It gives instructions for making protein called T-box 1. It plays an important role in tissue formation and organs during embryonic development.


Related Questions

Enter the sequence of the DNA coding strand with a 5-3 polarity. DO NOT WRITE 5 OR 3 OR 5' OR 3' IN THE BOX!

Answers

Complete question:

Use the sequence below to answer the following questions  

3’-ACGGATCCTCCCTAGTGCGTAATACG-5’  

5’-TGCCTAGGAGGGATCACGCATTATGC-3’  

1. Enter the sequence of the coding strand with a 5’-3’ polarity

Answer:

coding strand → 5´- GCATAATGCGTGATCCCTAGGCA -3´

Explanation:

When referring to the coding strand, we are talking about the sequence that turns to be the same as the mRNA that results from the transcription of the same DNI segment -switching bases T for U-.  

The coding strand receives that name because it is the sequence that codes for each amino acid composing the proteins.

When the DNI molecule separates into two strands to form the transcription bubble, we can identify two separate segments: coding strand and template strand.  

The coding strand goes in direction 5´ to 3´, while the complementary strand -template strand- grows in direction 3´ to 5´.  

Whenever we have a DNI molecule and we need to determine which strand is the coding one, we just need to look for the presence/absence of start or stop codons.

So, in the exposed example we have two strands, but we do not know yet which one is the coding one.

Conventionally, the first strand is always the coding one. However, let us analyze it by using the presence/absence of codons.

First-strand:

3’-ACGGATCCTCCCTAGTGCGTAATACG-5’

let us write it is 5´to 3´direction

5´- GCATAATGCGTGATCCCTAGGCA -3´

now let us identify the start and stop codons in 5´⇒3´direction.

Start codon ⇒ ATGStop codon ⇒ TAA, TAG, TGA

5´- GCATAATGCGTGATCCCTAGGCA -3´ ⇒ 1 start codon at the beginning

5´- GCATAATGCGTGATCCCTAGGCA -3´ ⇒ 3 Stop codons

Second strand: We will do exactly the same procedure

5’-TGCCTAGGAGGGATCACGCATTATGC-3’⇒ 1 start codon near the end

5’-TGCCTAGGAGGGATCACGCATTATGC-3’⇒ 1 stop codon at the beginning

What we did here was to identify in both provided strands, where the start and stop codons are placed. We can see that in the first strand we have the start codon near the beginning, while in the second strand we have it near the end of the sequence. From this information, we can assume that the first strand is the coding one. However, you need to know that some coding sequences do not have start and stop sequences, because they might correspond to a sequence in the middle of a gene.

So, the sequence of the DNA coding strand with a 5-3 polarity is

5´- GCATAATGCGTGATCCCTAGGCA -3´

The extinction vortex represents the idea that even if an organism is extant, it may have a gene pool that will not support its long-term survival.A. TrueB. False

Answers

Answer:

True.

Explanation:

Extinction vortex is a model used by scientists to understand extinction dynamics within a community. This model allows scientists to assess and understand how a population can become highly vulnerable to elements of its habitat, becoming increasingly apt for extinction. According to this model, any organism is capable of extinction, as all are susceptible to having a gene pool that will not allow its survival, regardless of the environment.

Most streams result from _____.
a. altitude
b. melted snow
c. oceans
d. rivers

Answers

Answer:

....b........ melted snow

C because I just took a test like that

animal cell vs plant cell

Answers

Answer:

animal cell

Explanation:

do you think there is the roots in utricularia?​

Answers

Answer:

I think so

Explanation:

What fraction of the progeny of the cross BbTt x BbTt will have black fur and long tails?

A) 0/16

B) 1/16

C) 3/16

D) 9/16

E) 16/16

Answers

Answer:

plzzzz upload a full picture

The only Purple Animal is the South African____?​

Answers

Answer:

Okapi

Mark Brainliest

okapi...

hopr helps uh

..yhnk my ansr

What is the purpose of a geological time scale ?

It used to predict natural disaters throughout Earth’s history.
It is used to present the correct sequence of events in the Earth’s history.
It is used to determine the absolute dates in years for different periods.
It used to create a naming system for flora and fauna.

Answers

Answer: B. It is used to present the correct sequence of events in the Earth’s history.

Explanation: On Edge!!!! :)

Answer:bbbbb

Explanation:

qcw3ec

14.
(GT.03)
Which of these best matches a source of information with its most reliable use? (2 points)


cladogram → date events which occurred in Earth's past

cladogram → study the evolution of organisms based on adaptations

fossil records → compare the evolution of completely soft-bodied organisms

fossil records → study the behavior of primitive animals in extreme weather conditions

Answers

Answer:

petrified fossils → date sedimentary rocks

does tomato have thick or thin exocarp?​

Answers

I think it’s thick

Explanation
Here, we describe the simultaneous transcriptome profiling of all five major cell types/tissues of the tomato fruit pericarp (Figure 1), including the outer epidermis (a single cell layer), collenchyma (approximately three to five cell layers in the Ailsa Craig cultivar used in this analysis), parenchyma

Which of these is a benefit of fish farming?

A. It can deplete native fish populations


B. It can restock lakes depleted by recreational fishing


C. It can pollute natural bodies of water


D. It can pass diseases to native fish populations

Answers

Answer:

The answer to this would be B

Explanation:

B:It can restock lakes depleted by recreational fishing

Which quantity does a light year measure

Answers

Answer:

distance = 9.46 trillion kilometers

Explanation:

Light years measure distance and is a unit that equals the distance light travels through space in one year on Earth (365 days) and is used as way to measure extremely vast distances in outer space. It equals 9.46 trillion kilometers.

Describe the impact of technology on the environmental today

Answers

Explanation:

Other detrimental effects include diseases such as typhoid and cholera, eutrophication and the destruction of ecosystems which negatively affects the food chain. Resource depletion is another negative impact of technology on the environment. It refers to the consumption of a resource faster than it can be replenished

The suprachiasmatic nuclei enable the nervous system to respond to daily light/dark alterations through their stimulation of

Answers

Answer:

The suprachiasmatic nuclei enable the nervous system to respond to daily light/dark alterations through their stimulation of melatonin.

Explanation:

Melatonin is a hormone produced naturally by the body. Its function is to regulate the body's circadian cycle. This hormone is stimulated and begins to act by changing between a light environment and a dark environment. This stimulation interacts with the suprachiasmatic nuclei making the nervous system understand this change and luminosity of the environment and respond to the action of melatonin.

Which of the following are structures of the
lymphatic system? Check all that apply.
Heart
Bone Marrow
Thymus
Spleen
Blood Vessels
Tonsils
Adenoids

Answers

Answer:Bone Marrow

Thymus

Spleen

Explanation:Bone Marrow

Thymus

Spleen

The following are structures of the lymphatic system -

Bone MarrowThymusSpleenTonsilsAdenoids

The lymphatic systemis a network of tissues, vessels, and organs.these structures work together to move a colorless, watery fluid called lymph back into your circulatory system (your bloodstream).The lymphatic system has the following structures:lymph nodes,spleen,thymus the lymphatic tissue found in the small intestine (Peyer's patches)adenoid tonsils,palatinetubal tonsils

Thus, the following are structures of the lymphatic system -

Bone MarrowThymusSpleenTonsilsAdenoids

Learn more:

https://brainly.com/question/16074605

why do males and females have different signs and symptoms when it comes to heart attacks

Answers

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For men and women, chest pain or discomfort is the most common heart attack symptom, but women are more likely to report shortness of breath, back or jaw pain, and nausea and vomiting. Black women of any age have a higher incidence of heart attacks than white women.

Women are less likely to need stenting to open a blocked artery, but they still suffer blood vessel damage that reduces blood flow to the heart, causing a heart attack.

Should we clone animals that are going or have gone extinct (in other words bring them back
either from the brink of extinction or from extinction)? Explain your answer.

Answers

No, God gives and takes away, the world is heartless and kills entire species to extinction but it’s nothing that God didn’t already know would happen. Dinosaurs are no longer here there extinct for a reason, nowadays extinction comes from man but everything that happens in this world is Already written out in Gods book

Answer:

I think we should but people are preventing this though

Explanation:

I think we should because it might benefit the world and let scientists to discover this animal. But then I don't think so because animals that are/were extinct could perhaps be from climate change. Nowadays, people don't take this matter seriously causing habitats to be destroyed and animals to be extinct :) Like icebergs are melting that mean penguins are at risk of being extinct,if we did something then this situation will be prevented. However dinosaurs did become extinct and they did not come back so its probably just life and this is how god planned it:)

If a diploid cell has 20 chromosomes, how many sister chromatids will be present
during PROPHASE of MITOSIS?

Answers

Answer:

92 chromatids

Explanation:

During phosphate, the nuclear envelope of the cell (which is where the 92 chromatids are contained) begins to break down. The centrioles, which are the only present in animal cells, separate and each moves to an opposite end of the cell

who do study edexcell certificate level? and can help be physics,chemistry and biology exam​

Answers

I have done GCSE sciences and also applied science a level so I could probably help you :)

What are the best management practices for Maize grain crop, by adopting which we can boost yield, elaborate in details your expert opinion.

Answers

Answer:

Cultivate prime grain and with timely care

The species Trichonympha ______________. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a may be isolated from the gut of termites where it is essential for cellulose digestion b is a ciliated organism c is a flagellated organism d both a and b e both a and c

Answers

c. is a flagellated organism

Write an experiment to show that sunlight is necessary for photosynthesis.

Answers

Answer:

Explanationwe have two or three plants, they both get the same water every day they both get the same amount of soil and fertilizer, one is without sunlight and one is with, after a 2 weeks our results will be found

hope this helps

Consider the following statements:
1. RNA is ribonucleic acid.
2. RNA is used for information transport (known as mRNA). Choose the correct answer from the given codes:
A Only 1
B Only 2
C Both
D Neither 1 nor 2
E None of the above

Answers

Answer:

Only A

Explanation:

RNA is used for storing and transporting information through mostly virus only..

Which genotype would give you a wild type phenotype?

Answers

Answer:

C

Explanation:

In the diagram below, which part of the human brain coordinates balance, movement, and other muscle functions so that the body moves smoothly? A B C​

Answers

Answer:

c

Explanation:

c is the cerebellum

b is the spinal chord

a is parietal lobe

Differentiate between pathogenicity and hypersensitivity; Also write different methods of inoculating the plants.

Answers

Answer:

As nouns the difference between pathogenesis and pathogenicity. is that pathogenesis is the origin and development of a disease while pathogenicity is the quality or state of being capable of causing disease.

State three ways of increasing the life-span of cut flowers​

Answers

Answer:

Clean your vase thoroughly, Keep flowers away from fruit, Flower Food and Water

Explanation:

At a birthday party, a teen decides to inhale some of the helium from a nearby balloon using his mouth. Before the helium gas reaches his right and left lungs, through which order of structures will it flow?
A. Oral cavity to the oropharynx to the trachea to the right and left main bronchi.
B. Oral cavity to the trachea to the trachea to the nasopharynx to the right and left main bronchi.
C. Oral cavity to the right and left main bronchi to the trachea to the oropharynx.
D. Oral cavity to the trachea to the larynx to the right and left main bronchi.
E. Oral cavity to the nasopharynx to the trachea to the right and left main bronchi.

Answers

Answer:

D. Oral cavity to the trachea to the larynx to the right and left main bronchi.

Explanation:

The respiratory system may be a system consisting of specific organs and structures used for gas exchange in animals and plants.

What is the process of respiration?

We have a pair of external nostrils opening out above the upper lips. It results in a nasal chamber through the nasal passage. The nasal chamber opens into the pharynx, some of which are the common passage for food and air. The pharynx opens through the larynx region into the trachea.Trachea is a straight tube extending up to the mid-thoracic cavity, which divides at the extent of the 5th thoracic vertebra into a right and left primary bronchi. Each terminal bronchiole gives rise to a variety of very thin, irregular-walled, and vascularized bag-like structures called alveoli. The branching network of bronchi, bronchioles, and alveoli comprise the lung.

Thus, we can conclude that the correct option is (e).

The oral cavity to the nasopharynx to the trachea to the right and left main bronchi.

You can learn more about the respiratory system here:

https://brainly.com/question/2619922

#SPJ2

How does water relate to the ability of a living thing to generate usuable energy?

Answers

Answer:

Without the proper balance of water, chemical reactions in cells could not take place.

Explanation: :)

2 True or False. A projectleie an object that once set in motion continues in motion by its own martia O True False ​

Answers

Answer:

The answer is true.Explanation:PARTICLES MOVING ALONG THE PATH POSSES A TWO DIMENSIONAL MOTION

MARK ME AS BRAINIST PLZ
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