There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that they can be harnessed to use the body's immune system to treat cancer. One study investigated the use of a T cell-engaging antibody, blinatumomab, to recruit T cells to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study) and after 20 days on blinatumomab for 6 subjects in the study. The difference (after 20 days minus baseline) is the response variable.
Baseline 0.04 0.02 0 0.02 0.38 0.31
After 20 days 0.18 0.37 1.1 0 0 0.34
Difference 0.14 0.35 1.1 -0.02 -0.38 0.03
Do the data give evidence at the 2% level that the mean count of T cells is higher after 20 days on blinatumomab? The test statistic is t = (±0.001)?

Answers

Answer 1

Answer:

1) First of all we have to state the null hypothesis and also an alternative hypothesis.

Null hypothesis: ud< 0

Alternative hypothesis: ud > 0

It is important to note that these hypotheses are constituting a one-tailed test.

2) Second thing is to formulate an analysis plan. And for that, the significance level must be set to 0.05. And by Utilizing sample data, we will conduct a matched-pairs t-test of the null hypothesis.

3) Thirs thing is to analyze sample data. By utilizng the sample data, we calculate the following:

standard deviation of the differences (s)standard error (SE) of the mean differencedegrees of freedom (DF)t statistic test statistic (t).

s = [tex]sqrt [ (\sum (di - d)2 / (n - 1) ][/tex]

s = 0.55324

Standard error = [tex]s / sqrt(n)[/tex]

Standard error = 0.2259

Degree of freedom = n - 1 = 6 -1

DF = 5

t statistic test statistic (t). = [tex][ (x1 - x2) - D ] / SE[/tex]

t statistic test statistic (t). = 1.55

Here di shows observed difference for pair i

d shows the mean difference between sample pairs

D shows the hypothesized mean difference between population pairs

n shows the number of pairs.

Hence we now have a two-tailed test

the P-value is the probability that a t statistic having 5 degrees of freedom is more extreme than 1.55; i-e less than - 1.55 or greater than 1.55.

Hence, the P-value = 0.182

Now interpret the results. As we know the P-value (0.182) is > (0.05) the significance level , Null hypothesis is accpeted.

We cannot reject H0. Which means that we are lacking evidence at the 5% level that the mean count of T cells is higher after 20 days on blinatumomab.


Related Questions

Opinión sobre la asistencia sanitaria en EEUU, la seguridad social en españa (estructura, prestaciones, etc...)

Answers

La Organización Mundial de la Salud clasifica al sistema de salud de pagador único de España como el séptimo más alto del mundo. Aparte de los medicamentos recetados, el plan proporciona una cobertura total como un derecho garantizado constitucionalmente, sin gastos de bolsillo.

En España, la tasa media de la seguridad social es alta, con cotizaciones fijadas en el 28,3 por ciento. La mayor parte del tiempo, el empleador soporta la mayor parte de la carga financiera. Los autónomos están obligados a abonar íntegramente sus propias cotizaciones españolas, pero en un porcentaje global inferior.

Army of youth and students in support on Zedong
A. Bolsheviks

B. Black Hand

C. Green Revolutionists

D. Red Guard

Answers

Answer:

D. Red Guard. .................

Which of the following Chinese dynasties was know for having a good government that cared for the people? A.Qin Dynasty B.Tang Dynasty C.Zhou Dynasty D.Han Dynasty

Answers

D, the Han Dynasty.

To help emergency vehicles reach those in need, __________
A. Stay Alert.
B. Investigate.
C. React.
D. all of the above

Answers

Answer:

i think is c

Explanation:

the answer is all of the above

6. What did the Japanese official mean when he said, "I am afraid that we have
awakened a sleeping giant"?

Answers

Answer:

Japanese Admiral Isoroku Yamamoto

Explanation:

The Supreme Court is best characterized as
a federal court.
an appellate court.
a judicial court.
a inferior court.

Answers

The correct answer is B. An appellate court.

Explanation

The Supreme Court of the United States is the highest judicial court in that country. This entity is made up of a president and eight associate judges who are chosen by the president and subsequently validated by the Senate.

Among the functions of the Supreme Court are judicial review and the power to declare unconstitutional federal or state laws and acts of the federal and state executive powers. Likewise, decisions made by the Supreme Court cannot be appealed.

On many occasions, the Supreme Court has the function of being an appeals court because it resolves appeals made against decisions made in district courts and other cases of federal courts. Therefore, the correct answer is B. An appellate court.

Answer: an appellate court

source: trust me bro

what are the three factors that determine an object's mechanical energy

Answers

Answer: 1.) motion(kinetic)

               2.) position above ground(gravitational potential)

                3.) deformation(strain)

Explanation: hopes this helps also let e know if you need any more help

is the term used to describe the amount of control or influence that consumers have on a market.
Sovereignty
Competition
Oligopoly

Answers

Answer:

The term is used in describing the amount of control or influence that consumers have on the market is sovereignty

Explanation:

How does a bill passed by Congress become law? A) It is ratified by each state. B) It is ratified by a popular vote of all citizens. C) The Supreme Court judges that it is a good law. D) The president signs it.

Answers

Answer:

D the president has to sign it

Explanation:

I need help with this

Answers

Answer:

can you send a link so I can do it and give you answers

Explanation:

Match each element of a technical writing portfolio to its purpose.

Answers

Answer:

Sample Summaries - to provide an idea of the target audience and the problem solved

Resume - to highlight achievements , skills , and experience

Writing Samples - to demonstrate the ability to create effective documentation

Explanation:

I just took the test. Got it right 100%.

Is among us dead now?

Answers

Answer:

Pretty much

Explanation:

I still play :D

No it’s still going

A set of rules or laws that guide how a country or state works- A.constitution
B.preamble
C.veto

Answers

Answer:

A. sorry if i’m wrong!

Explanation:

"Texans believed annexation offered an easier solution to most of the problems facing the Republic than accomplishing hard tasks involved in building a new nation. Few Texans dreamed of a future as an independent nation. Most looked forward to joining the United States, and Texans did so at their earliest opportunity." Which of the following statements best describes the role of slavery in the path to achieving the goals described in the passage?

A. Texas's unwillingness to support slavery led to the South to resist.

B. Taxas's willingness to compromise on the slavery issue hastened annexation.

C. Taxas's potential admission as a slave state caused controversy and delayed annexation.

D. Texas's agriculture resources convinced the North to compromise on slavery and approve annexation.

Answers

Answer:

A

Explanation:

The state of Texas Annexation was a time of slavery and hardship to the south and was seen as a state that had more resources to offer in terms of slavery.


In a criminal court case, the prosecutor is the person who?
O goes on trial for potentially committing a felony or misdemeanor.
O claims that a suspect has committed a felony or misdemeanor.
O has committed a tort that has wrongly harmed someone else.
O was wrongly harmed by someone who committed a tort.

Answers

Option 2:

Claims that a suspect has committed a felony or misdemeanor.

__

Defendant: goes on trial for potentially committing a felony/misdemeanor.

Tortfeasor: committed a tort.

Plaintiff: wrongly harmed by someone who committed a tort.

What was the impact of the battle of Lexington and concord

Answers

Answer:

The Revolution Begins: The Aftermath of the Battles of Lexington and Concord. The Battles of Lexington and Concord took a toll on both sides. For the colonists, 49 were killed, 39 were wounded, and five were missing. For the British, 73 were killed, 174 were wounded, and 26 were missing.

Explanation:

Which of the following statements is true?

The federal government creates all state and local laws.
State and local governments may overlap in providing some services.
There is a strict divide between which services are provided by the state or by local government.
Local governments may not pass any laws.

Answers

State and local governments may overlap in providing some services.

State and local governments assist each other with services like law enforcement, welfare, education, and etc.

What was one of the goals of the US occupation of Japan after World War II

Answers

Answer:

On September 6, US President Truman approved a document titled "US Initial Post-Surrender Policy for Japan". The document set two main objectives for the occupation: eliminating Japan's war potential and turning Japan into a democratic nation with pro-United Nations orientation.

Answer:

one of the goals was to prevent the Japanese from expanding their ideology and political agenda into the rest of Asia. The US interfered because they were threatened by the power Japan was expanding and gaining.

At the beginning of the Great Depression, which president did many Americans blame for their problems?

Answers

Answer:

President Hoover

Explanation:

President Herbert Hoover

Explanation:

They blamed Hoover for the depression because he was doing nothing to end it. They thought the government should help them. But, Hoover believed it was up to Private individuals and institutions to offer help, and not the government.

When voting in an election, what characteristics would you look for in someone running for president?

Answers

Answer:I feel that a candidate running for president should be a good leader, instead of a follower. That person should also be healthy. Our president should be a patriotic citizen and a very good negotiator. Our president should be well experienced in government policies. We need a person who promotes education, and who wants to help the middle class working people.

Explanation:

What are the political, cultural, and economic forces that threaten the matrilineal orientation of the Minangkabau?

Answers

Answer:

political

Explanation:

it was the first time I have to go near about the futureand time to get the future and I will get the information from my account

Which of the following BEST explains why Japan has a high gross domestic product when it has few natural resources?

A.
Japan has placed tariffs on foreign goods which allows consumers to pay lower prices because goods are produced domestically.

B.
Japan can purchase many goods internationally to make up for their lack of natural resources.

C.
Japan relies on natural resources found in the ocean to make up for its lack of resources on land.

D.
Japan has invested in capital goods and human resources to make it a larger producer of finished goods for trading.

Answers

Answer: D

Explanation: Because When Japan was Making up it's lack of Natural Resources They Used All the Money they had and Invested In Human Capital and Capital Goods And Japan is a High Country with a Really High GDP and What they Did before They Invested was They Sold Their Resources and Bought Them Back for a Higher Price when they Were Refined and Then Japan Placed it's Factories in The USA and Many Other Countries. Japan Put their Factories That Produced Cars Like FORD,TESLA,TOYOTA,DATSUN,SUBARU,HONDA,MAZDA,CHRYSLER,MITSUBISHI,NISSAN,CHEVROLET. That's How They Got Their Country's GDP and Literacy Rate and Standard of living So High.

Your Welcome

Sincerely Eric

Japan has a high gross domestic product when it has few natural resources because D.Japan has invested in capital goods.

What is Gross domestic product?

Gross domestic product serves as the standard measure of the value added in a country which is been done through the production of goods.

Therefore, Japan has a high gross domestic product because she invested in capital goods and human resources.

Learn more about Gross domestic product at;

https://brainly.com/question/1383956

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is it necessary for California to have both the ICS and SEMS? ​

Answers

Answer:

To respond to frequent and multiple disasters that occur at any time and anywhere in the state, it is important that emergency response agencies operate within a clear and consistent organizational structure. Public agencies are increasingly forced to manage the costs of emergencies more effectively with fewer resources. Many different agencies must work together effectively to protect lives, property, and the environment during disasters. SEMS facilitates priority setting, inter-agency cooperation, and the efficient flow of resources and information.

SEMS is the cornerstone of the California emergency response system and the fundamental structure for the response phase of emergency management. The system unites all elements of the California emergency management community into a single integrated system and standardizes key elements.

Incident Command System (ICS): an emergency response system at the field level based on management by objectives

Multi / interagency coordination: Affected agencies working together to coordinate resource allocation and emergency response activities.

Mutual Aid: A system to obtain additional emergency resources from unaffected jurisdictions.

Explanation:

Operational area concept: the county and its subdivisions to coordinate damage information, resource requests and emergency response. California law defines the Operating Area (OA) as all political jurisdictions within the limits of a given county. Since the near response is preferred over the farthest response, the necessary resources are sought first within the Operational Area. Since the AB does not exist, other than as a planning structure, someone must fulfill the role when necessary. Usually this is the county government. The Yolo County EOC, in addition to directly supporting operations in unincorporated areas, acts as the operational area EOC to facilitate requests for resources and information among the county, cities, and special districts. If the resource cannot be found within the OA, a request is made to the next higher level.

The California Emergency Management Agency (CalEMA) has divided California into six mutual aid regions, each of which is assigned to one of the three administrative regions. Yolo County is in Region IV Mutual Aid Region, part of the Interior Administrative Region. If the resource cannot be found within the Region, a request is made to the next higher level.

State: At this point, the request is made to other regions of the state to find the necessary resource.

Similar to requests for resources, information flows along the same chain. This allows CalEMA to know what is happening across the state, while keeping communications manageable. Similarly, they can distribute information across the chain.

Other aspects of SEMS include the Incident Command System (ICS), a structure for organizing a response. SEMS also includes the Unified Command concept, where all agencies responding to the scene of an incident coordinate their actions as a single plan, rather than multiple efforts taking place at the same location.

Explanation:

Answer:

Local agencies are encouraged to implement SEMS, but are not required to do so under law. Use of SEMS by local government agencies is required to obtain state reimbursement for response related personnel costs.

Explanation:

Which of the following risks is typically associated with an outdoor environment? a. asbestos b. cleaning products c. pesticides d. dust Please select the best answer from the choices provided A B C D

Answers

Answer: The answer is A

Explanation:

Answer:

C- Pesticides

Explanation:

Right on edge 2021

If you wanted to find out the average temperature in Africa, what kind of map would you use?

Answers

Answer: Basically it depends on the elevation:

The field of geography relies on many different types of maps in order to study the features of the earth. Some maps are so common that a child would recognize them, while others are used only by professionals in specialized fields. Some of the most common types are political, physical, topographic, climate, economic, and thematic maps.

Types of Maps

Simply defined, maps are pictures of the Earth's surface. General reference maps document landforms, national boundaries, bodies of water, the locations of cities and so on.

Thematic maps display specific data, such as the average rainfall distribution for an area or the distribution of a certain disease throughout a county.

Political Maps

A political map does not show topographic features like mountains. It focuses solely on the state and national boundaries of a place. These maps also include the locations of cities large and small, depending on the detail of the maps.

A typical example of a political map would be one showing the 50 U.S. states and their borders along with the United States' international borders.

Physical Maps

A physical map is one that documents landscape features of a place. These maps generally show things like mountains, rivers, and lakes. Bodies of water are commonly shown in blue. Mountains and elevation changes are sometimes shown with different colors and shades to show elevation. On physical maps, greens usually indicate lower elevations while browns usually indicate higher elevations.

This map of Hawaii is a physical map. Low elevation coastal regions are shown in dark green, while the higher elevations transition from orange to dark brown. Rivers are shown in blue.

World Map 3D Render Topographic Map

World Map 3D Render Topographic Map. FrankRamspot/Getty Images

Topographic Maps

A topographic map is similar to a physical map in that it shows different physical landscape features. Unlike physical maps, though, this type of map uses contour lines instead of colors to show changes in the landscape. Contour lines on topographic maps are normally spaced at regular intervals to show elevation changes (e.g. each line represents a 100-foot elevation change). When lines are close together, it means the terrain is steep.

Climate Maps

A climate map shows information about the climate of an area. These maps can show things like the specific climatic zones of an area based on the temperature, the amount of snow an area receives, or the average number of cloudy days. These maps normally use colors to show different climatic areas.

This climate map for Australia uses colors to show differences between the temperate area of Victoria and the desert region in the center of the continent.

Vegetation zones of the world, lithograph, published in 1897

Vegetation zones of the world, lithograph, published in 1897.  ZU_09/Getty Images

Economic or Resource Maps

An economic or resource map shows the specific types of economic activity or natural resources present in an area through the use of different symbols or colors depending on what is being depicted.

This economic activity map for Brazil, for example, uses colors to show different agricultural products of given areas, letters for natural resources, and symbols for different industries.

Road Maps

A road map is one of the most widely used map types. These maps show major and minor highways and roads (depending on the degree of detail), as well as things like airports, cities, and points of interest such as parks, campgrounds, and monuments. Major highways on a roadmap are generally shown with thick, red lines, while minor roads are lighter in color and drawn with narrower lines.

A road map of California, for example, would depict Interstate highways with a wide red or yellow line, while state highways would be shown in a narrower line in the same color. Depending on the level of detail, the map may also show county roads, major city arteries, and rural routes. These would be depicted in shades of gray or white.

Thematic Maps

A thematic map is a map that focuses on a particular theme or special topic. These maps are different from the six aforementioned general reference maps because they do not just show features like rivers, cities, political subdivisions, elevation, and highways. If these items appear on a thematic map, they are background information and are used as reference points to enhance the map's theme.

This Canadian map, for example, which shows changes in population between 2011 and 2016, is a good example of a thematic map. The city of Vancouver is broken down into regions based on the Canadian Census. Changes in the population are represented by a range of colors ranging from green (growth) to red (loss) based on the degree of change.

I NEED HELP ASAP.
ILL GIVE YOU 20 POINTS

Answers

Answer:

bet

Explanation:

why do we need the fundamental rights?

Answers

Answer:

Fundamental Rights protect the liberties and freedom of the citizens against any invasion by the state, prevent the establishment of the authoritarian and dictatorial rule in the country. They are very essential for the all-round development of the individuals and the country.

Answer: Fundamental Rights protect the liberties and freedom of the citizens against any invasion by the state.

what two laws that protect citizen against the human trafficking

Answers

Explanation:

Trafficking Victims Protection Reauthorization Act of 2003. Trafficking Victims Protection Reauthorization Act of 2005. Trafficking Victims Protection Reauthorization Act of 2008. Trafficking Victims Protection Reauthorization Act of 2013 (Title XII of the Violence Against Women Reauthorization Act of 2013)

Please help me match the correct definition to the vocabulary words -Asap giving 20 points!!

Answers

Answer:

Boom-  Economic Growth

Black Gold- Term for oil

Derrik- Large framework or tower

Reserve- A supply of nat. recorces that have not been used

Explanation:

What is the difference between wisdom and knowledge

Answer:
Knowledge is the accumulation of facts and ideas.

Wisdom is knowing how to apply those facts and ideas so that important choices can be made

Answers

The difference between wisdom and knowledge we are gave us the answer knowledge is an accumulation of facts wisdom is knowing how to play those facts and ideas so that important choice will be made I'm not really sure what the question is if you already gave the answer but never mind bye
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