TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP?
a. Reduced siRNA-mediated mRNA degradation
b. Increased miRNA-mediated translational repression
c. Increased deadenylase-mediated mRNA degradation
d. Reduced proteasome-mediated protein degradation

Answers

Answer 1

Answer:

a. Reduced siRNA-mediated mRNA degradation

Explanation:

The TRBP (transactivation response element RNA-binding protein) is an RNA-binding protein that forms the Dicer complex, which is involved in epigenetic pathways such as those mediated by the RNA interference (RNAi) mechanism. RNAi is a key process where small non-coding RNAs such as, for example, small interfering RNAs (siRNAs) and microRNAs (miRNAs) can inhibit target gene expression at posttranscriptional level by different mechanisms (including the degradation of target mRNAs). A null mutation of this cofactor will alter the Dicer complex, thereby also affecting RNAi pathways mediated by small interfering RNAs.


Related Questions

Which of these statements most accurately describes currencies in North America

Answers

Answer:

North American countries have done away with separate currencies. Each country in North America uses its own currency. 2. See ...

A couple has just learned their neonate is diagnosed with osteogenesis imperfecta, and they
ask, "What caused our child to get this disease?" What should the health care provider teach
the couple about their neonate's condition?

Answers

Answer:

osteogenesis imperfecta is an inherited genetic disease that mainly affects the bones.  

Explanation:

Osteogenesis imperfecta is an inherited genetic disease associated with alterations in collagen synthesis, which have been shown to increase the risk to suffer bone fractures. This genetic disorder is characterized by different health problems including, among others, fragile bones, reduced skeletal mass, skin hyperlaxity, malformations in the central nervous system, etc. Clinically, osteogenesis imperfecta must be managed by an interdisciplinary medical team, since patients may present a clinical picture ranging from mild to lethal. In the first place, it is imperative to provide health care to avoid fractures, exercises to maintain muscle mass, exercise to improve motor skills, skincare by specialized dermatologists, etc.

The disease 'osteogenesis imperfecta' is caused by the neonate inheriting it

from either of the parent because it's a genetic disorder. The health care

provider should teach the parent about how to prevent the effect of having

such disease such as bone fractures.

Osteogenesis imperfecta is a genetic disorder inherited by offspring from

their parent. The disease involves individuals having very  brittle bones which are easily broken. The nurse should teach the parent to adopt bone strengthening steps such as adequate calcium intake and physiotherapy.

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After entering a dark room, you turn on a light switch, but the light does not come on. Please suggest three different hypothesis that might explain your observation. Please also note how you might test these hypotheses and describe what observation(s) may lead you to conclude that one of the hypothesis is correct.

Answers

Answer:

First hypothesis; may be the power is cut. ( no power supply) Second hypothesis; may be the light switch is defective ( wall switch not working )Third hypothesis; maybe the bulb is burnout  ( light bulb may not be working )

Explanation:

The three possible hypothesis for light not to turn on immediately after one on the switch are;

First hypothesis; may be the power is cut. ( no power supply) Second hypothesis; may be the light switch is defective ( wall switch not working )Third hypothesis; maybe the bulb is burnout  ( light bulb may not be working )

We test the first hypothesis, how?

We check if other electronics connected to the same sources of power supply as the bulb is working. If the electronics are not working, then the first hypothesis is correct but if they are working then the hypothesis fails and we move on to test the next hypothesis.

To test for the second hypothesis as the first hypothesis fails, we remove the bulb and fix it into another socket which has a working switch. If the bulb comes on then the second hypothesis is correct but if the bulb does not turn on then the hypothesis fails so we move on to test the third hypothesis.

As the bulb fails to turn on in our initial socket and a second bulb is fixed in that same socket and it came on, then the third hypothesis is correct.

The three hypotheses we can derive from entering a dark room, turning on a

light switch,and the light not coming on include

There may be no power source at that momentThe bulb may be faultyThe switch may be faulty

A power source helps to provide energy to power up an appliance and where it is absent, the bulb won't light up.

A defect in the switch and bulb may also hinder the light from coming on as

the switch controls electric current flow while the bulb produces the light.

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the origin of a muscle is generally

Answers

explain the  question more

Answer: The stable and proximal attachment

Explanation:

Without this, many cycles such as the water cycle and photosynthesis would not exist. What could all these cycles not exist without?

Answers

Answer:

This question appears incomplete

Explanation:

This question appears incomplete. However, one similar substance that, if missing, many cycles (particularly the two cycles/processes provided in the question) will not exist/proceed is the sun/sunlight.

In the water cycle for instance, if there is no sun/sunlight, there will be no heat to allow for evaporation of water from the water-body (ocean, sea, stream or lake) hence there will be no cloud of water droplets in the atmosphere. The implication of this is that, the first process of the water cycle will not proceed, hence the cycle will not exist.

During photosynthesis, carbondioxide reacts with water in the presence of sun/sunlight to produce glucose and oxygen. The absence of sun in this reaction will not lead to the production of glucose which is the useful product of photosynthesis for plant.

From the explanation above, it can be deduced that the absence of the sun/sunlight will prevent the two cycles from existing.

You put 10ul (one loopful - the loop is calibrated for this volume) of a 0.03 ug/ul pGLO solution into the DNA tube. Calculate the ug of DNA you put into the tube.

Answers

Answer:

The µg of DNA put into the tube is 0.3 µg.

Explanation:

Here in this question, we are interested in calculating the µg of DNA put into the DNA tube.

This can be calculated using a mathematical formula.

Mathematically;

Total amount of DNA in µg = concentration in µg/ µl X volume in µl

= 10 µg/µl X 0.03µl = 0.3 µg.

What is the correct formula for population growth? A. D+B-I-E B. E+D-B-I C. B+I-D-E D. I+E-B-D

Answers

Answer:

C.) B+I-D-E

Explanation:

The correct formula for population growth is the individuals added to the population via birth or immigration, minus the individuals removed from the population via death or emmigration. Therefore the answer is (B+I)-(D+E), or B+I-D-E

If the Gulf Stream stopped running, how would the climates of North America and Europe be affected?

Answers

Answer: Land would become infertile, habitat loss, & environmental changes

Explanation:

Because there wouldn't be alot of water to keep the soil moist, therefore the ground would begin to harden and get dry. :)

If the Gulf Stream stopped, the climates of North America and Europe would be colder and drier.

The gulf stream is a huge current of warm and fast-moving ocean water. This ocean current plays a key role in regulating temperatures across the globe and has an impact on the frequency and intensity of storms and rainfall. The collapse and stoppage of this stream will cause an array of problems, including but not limited to:

Reduced rainfallLower temperaturesFewer storms

Areas that would be particularly affected by this are North America and Europe. This is due to the direction that the gulf stream flows, carrying warm water along these boundaries.

The vast amount of warm water carried by this stream explains how it is able to affect the average temperatures of these coastal areas, with the disappearance of the stream, temperatures in North America and Europe would initially decrease.

The warm water carried by this current is also responsible for increased rainfall. Warm water on the surface of the ocean is heated by the sun and evaporates, creating clouds, which then provide rain. The absence of this current would dramatically affect cloud formation and reduce the amount of rain severely. This can lead to droughts and reduced agriculture.

Though Fewer storms may seem like a positive impact, it is not entirely. Storms play a crucial part (together with ocean currents) in regulating global temperatures, as well as provide a source of rainfall to end droughts and promote biodiversity in areas that depend on water and humid climates.

The gulf stream is important for maintaining climates and rainfall. If it were to stop, climates in North America and Europe would be colder and drier.

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Which of the following is a testable scientific question

Answers

Where are the questions so i can answer them?

Answer: Just took the test: Its "How does the age of city affect the number of trees in the city? "

Which of the following best describes how crossing over occurs during meiosis?

Answers

Answer:

first give the following options bro..

Type the correct answer in the box. Spell all words correctly. Henry went on a field trip to a national park. He not only observed the aquatic life in the pond, but also the trees, vegetation, and animal’s species on land. Which type of diversity did Henry come across in the national park? Henry came across the______ diversity.

Answers

Answerflora

Explanation:

If bacteria transformed with a recombinant pUC18 plasmid produce white colonies when grown on plates containing ampicillin and Xgal, which of the following is least likely?

a. They produce β-lactamase that provides resistance to ampicillin.
b. They carry a vector that contains a DNA fragment inserted into the multiple cloning site.
c. They produce functional β-galactosidase that cleaves X-gal.
d. They carry a vector with a lacZ gene that has been disrupted and rendered nonfunctional.
e. They carry a vector with the bla gene used as the selectable marker.

Answers

Answer:

c. They produce functional β-galactosidase that cleaves X-gal.

Explanation:

β-galactosidase is an enzyme capable of catalyzing the enzymatic hydrolysis of β-galactosides into monosaccharides by hydrolyzing the β-glycosidic bond. On the other hand, X-gal is an analog of lactose composed of galactose, which is widely used in laboratories for the detection of β-galactosidase. In the presence of β-galactosidase, X-gal is hydrolyzed by cleaving its β-glycosidic bond, thereby confirming the presence of β-galactosidase.

Intrinsic factor A. increases gastric motility. B. causes the release of stomach acid. C. facilitates the absorption of vitamin B12. D. protects the stomach lining from the effects of stomach acid. E. stimulates the synthesis of DNA.

Answers

Answer:

C. facilitates the absorption of vitamin B12.

Explanation:

The Intrinsic factor is a substance that is produced by the stomach and it has the important function of producing vitamin B12 which is necessary for life. Vitamin B12 is used in the production of mature red blood cells. It also improves the function of the nervous system. The production of this intrinsic factor is a very vital role of the stomach because, in the absence of a stomach, for example, in the case of a gastrectomy, a person can only survive if he is given injections of Vitamin B12.

The stomach also serves as a holding center for food and eventually delivers the food to the small intestine and the duodenum.  

Which macromolecule forms a double layer as the primary structure of cell membranes?
fats
oils
phospholipids
steroids​

Answers

Answer:

phospholipids

Explanation:

Answer:

C. phospholipids

Explanation:

The other person said it

Predict what will happen to the following lung volumes and capacities during strenuous exercise. Assume that you are comparing from a baseline of normal resting respiration.


Lung Volume or Capacity Predicted change from resting baseline : Use Increase, Decrease or No Change

TLC (total lung capacity)
No change
VC (Vital capacity)
IC (Inspiratory capacity)
FRC (Functional residual capacity
TV (Tidal volume)
IRV (Inspiratory reserve volume)
ERV (Expiratory reserve volume)
RV (Residual volume)

Answers

Answer:

During intense exercise:

lung capacity increases

vital capacity increases

respiratory capacity increases

functional residual capacity increases

tidal volume increases

the inspiratory and expiratory reserve volumes decrease as does the residual volume.

Explanation:

Residual volumes decrease because having better lung capacity, better development of the secondary skeletal muscles that collaborate in expiration and inspiration, these are given in a better way, and more effectively.

If these processes take place more efficiently, their potentiality increases and expiration and inspiration move a large current of air into the lungs, thus leaving less reserve airs.

Those people who have increased exhalation or inspiration reserve, have a weak activity of the musculature in the processes and function as "stagnant air" which is synonymous with a lack of physical activity or aerobic capacity.

It is important to clarify that all the above processes are accompanied by an increase in the size of the chest cage

Which organisms transform nitrogen to a form that is useful to plants?
bacteria
animals
fungi
humans​

Answers

Answer:

Bacteria

Explanation:

Nitrogen fixation is the step of the nitrogen cycle that occurs with the help of microbes. Bacteria transform the nitrogen into a usable form for the plants. Thus, option a is correct.

What are nitrogen-fixing bacteria?

The nitrogen cycle is the part of the biogeochemical cycle that converts nitrogen into other forms that can be used by plants. The nitrogen is converted through the nitrogen-fixing bacterias.

The nitrogen-fixing bacterias are heterotrophic in nature that lives freely in the soil. A few examples are Bacillus, Azotobacter, Clostridium, etc. These bacterias transform the atmospheric nitrogen into usable compounds called ammonia which is the fixed nitrogen and can be used by the plants.

Therefore, nitrogen-fixing bacterias transform nitrogen.

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This category of plants does not have vascular tissue or seeds. Question 3 options: Angiosperms Gymnosperms Ferns Mosses

Answers

Answer:

Mosses

Explanation:

Mosses are the category of plants that does not have vascular tissue or seeds while angiosperm, gymnosperms, and ferns have vascular tissues and seeds.

Due to absence of vascular bundles or veins, the mosses also lack stems, true roots, and leaves. some of the examples of mosses are: liverworts, hornworts, and Ricceia natans etcetera.

Hence, the correct answer is "Mosses".

Answer:

Mosses

Explanation:

Mosses are the category of plants that do not have vascular tissue or seeds. Ferns do not have seeds, but do have vascular tissues. Angiosperms and gymnosperms have vascular tissue and seeds.

Is it normal to have two baby fish that are stuck together?

Answers

Answer:

No its not

Explanation:

Hey there!

Conjoined fish is a very rare occurrence that does not happen often.

Hope this helps :)

An sixty-year-old man has painful fluid-filled vesicles that have begun crusting over in a wide band across the left side of his lumbar area. He has a history of chickenpox. Based on this information, the likely disease is which is caused by:________

a. scabies, Pediculosis humanus
b. fever blisters, HSV-1
c. impetigo, Staphylococcus aureus
d. German measles, Rubella
e. shingles, varicella-zoster virus

Answers

Answer: shingles, varicella-zoster virus

Explanation:

It should be noted that shingles usually occur with old people and it causes a painful rash when the chicken pox virus is reactivated in the body.

Since the man is old and has painful fluid-filled vesicles that have begun crusting over in a wide band across the left side of his lumbar area and also has a history of chickenpox, it's very likely it is shingles.

Choose a strategy to clone genes known only by a mutant phenotype in organisms with highly efficient transformation procedures and relatively small genomes.

Answers

Answer:

By combining traditional genetic mapping with whole-genome sequencing (next-generation sequencing)

Explanation:

Map-based cloning, also named positional cloning, is a technique used to identify genetic sequences linked to markers whose exact physical localization in the genome is known. Map-based cloning has shown to be useful to clone genes, however, this approach is limited to the existence of mutant phenotypes in different organisms/accessions/strains. In recent years, map-based cloning has been combined with next-generation sequencing methodologies in order to clone genes in background of single mutants without information on multiple organisms. This type of strategy has the potential for identifying causal mutations and thus clone genes in species with small genomes and high transformation efficiencies such as, for example, Arabidopsis thaliana.

in the krebs cycle,

a. pyruvate is broken down into Co2 molecules
b. glucose is broken down into NADH and CO2
c. Co2 is concerted in pyruvate and O2
d. NADH and CO2 are converted into ATP

Answers

Answer:

a. pyruvate is broken down into Co2 molecules

Explanation:

Krebs cycle is also known as Citric Acid Cycle, in which pyruvate formed during the glycolytic is broken down into Carbon Dioxide (CO2) and Water (H2O).

Each pyruvate molecule is broken down into carbon atom which releases carbon dioxide.

Hence, the correct answer is "a. pyruvate is broken down into Co2 molecules".

Which of the following can a chemical bond do?
A. Change element properties
B. Store energy
OC. All of these
D. Release energy

Answers

Answer: C

Explanation:

The following can a chemical bond do is all of these. The correct option is C. All of these.

What is a chemical bond?

A chemical bond is a bond formed between two elements. The energy of the reaction is stored in the bonds when the reaction happens, the energy is released from the bonds. It also changes the chemical properties of the elements.

Thus, the correct option is C. All of these.

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A cross-sectional view of a log shows a concentric pattern. Which part of the stem gives rise to this pattern?

Answers

A cross-sectional view of a log shows a concentric pattern. Which part of the stem gives rise to this pattern?

B. Xylem

as it contribute for most of a tree's growth in diameter.

Which of the following groups could be identified using the biological species concept? Select all that apply. Select all that apply. bacteria living today extinct dinosaurs sunflower species living today lizard species living today

Answers

Answer:

Bacteria, Sunflowers, Lizards.

Explanation:

They are all biological species due to being apart of flora and fauna. It wouldn't be dinosaurs since biologists study living things, dinosaurs are extinct.

The groups 'sunflower species living today' and 'lizard species living today' could be identified using the biological species concept.

The biological species concept defines a species as a special group of interfertile individuals.

These individuals can then cross in order to produce fertile offspring and thus perpetuate the species.

The biological species concept was developed by the biologist Ernst Mayr.

In conclusion, the groups 'sunflower species living today' and 'lizard species living today' could be identified using the biological species concept.

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Each of two parents has the genotype blue/brown​, which consists of the pair of alleles that determine eye color​, and each parent contributes one of those alleles to a child. Assume that if the child has at least one blue ​allele, that color will dominate and the​ child's eye color will be blue. a. List the different possible outcomes. Assume that these outcomes are equally likely. b. What is the probability that a child of these parents will have the brown/brown ​genotype? c. What is the probability that the child will have blue eye color​?

Answers

Answer:

See the answer below.

Explanation:

Let the allele for eye color be represented by A. Blue is dominant over brown eye color, hence, blue allele would be A while brown eye allele would be a.

Two parents have the genotype blue/brown which is equivalent to Aa.

                   Aa    x    Aa

    AA               2Aa                aa

 blue eyes     blue eyes         brown eyes

a. Different possible outcomes: AA blue eyes, Aa blue eyes, and aa brown eyes.

b. Probability of a child from the cross having brown/brown (aa) genotype = 1/4 or 25%

c. Probability that the child would have blue eye color = 3/4 or 75%

The root of mutualism, mutual,
means...
A. together.
B. alone.
C. only.​

Answers

Answer:

A. Together.

Explanation:

The root word of mutualism, mutual means together or a thing that many people share.

For example:

Mutualist Symbiotic Relationship refers to a relationship in which organisms are benefited, in other words it is a win-win.

The relationship between the Egyptian plover bird and the crocodile, that is mutualist relationship.

When a meat or something (food) gets stuck in the teeth of the crocodile then the Egyptian plover bird takes it out (like a toothpick).

The crocodile gets benefited.

The bird also gets benefited (its gets its food)

Hope this helps ;) ❤❤❤

Answer:

together

Explanation:

Mutualism is defined as a relationship that benefits two organisms, or it is defined as a doctrine in sociology where mutual aid is beneficial to society and the individual. An example of mutualism is pollination which is when bees take nectar from flowers and then deposit the nectar on another flower.

What is the only source of energy production for RBCs?

Answers

Answer:

Anaerobic oxidation of glucose

A layer of cells called the endodermis surrounds the stele. Xylem is found towards the center of the stele and phloem towards the outside of the stele. 18) How does this compare to their arrangement in the stem? 19) The meristematic region is protected in the root by the presence of a root cap. How is the meristematic region protected in the stem tip? 20) In which of these regions would you expect to find the specialized cells of vascular tissue? 21) In which of these regions are the cells genetically identical? 22) Why?

Answers

Answer:

Epidermis layer is responsible for the protection of meristematic region.

Explanation:

Meristematic region is protected in the stem tip by epidermis which consist of dead layer of cells. Epidermis is the outer layer of stems, leaves, flowers and fruits which is responsible for the protection of inner part from damage. Vascular bundle such as phloem present near the boundary of the stem while the xylem is present in the inside of the stem. In the inside layer of the stem, all the xylem cells are genetically identical while the layer that is present at the edge of the stem is phloem in which all the cells are  genetically identical to each other.

How does the movement of particles of matter change when temperature increases?
Decreases
Increases
Increases then decreases
Does not change

Answers

Answer:

Increases

Explanation:

The movement of particles of the matter increases with the increase in temperature.

The particles gain kinetic energy with increasing temperature and move in faster rate.

For example: When we blow a balloon with our mouth, we increases the temperature inside the balloon, the particles in the balloon gain kinetic energy that leads to the faster movement of gas particles in the balloon and they collide with each other and surface of balloon, after a peak the balloon get burst because of high kinetic energy and high collision.

Hence, the correct answer is "increases".

After the centromeres separate during mitosis, the chromatids, now called _______, move toward opposite poles of the spindle.

Answers

Answer:

Daughter chromosomes

Explanation:

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A person can see clearly up close but cannot focus on objects beyond 75.0 cm. She opts for contact lenses to correct her vision. (a) Is she nearsighted or farsighted? (b) What type of lens (converging or diverging) is needed to correct her vision? (c) What focal length contact lens is needed, and what is its power in diopters? Who was Hernando de Soto? (quick summary would be extremely helpful!) What is a hyperbole comparing a cloud and pillow A project with an initial cost of $27,250 is expected to generate cash flows of $6,600, $8,700, $9,100, $8,000, and $7,400 over each of the next five years, respectively. What is the project's payback period? What is Bolivia's population made of?mainly Asian descendantsmainly European descendantsmainly African American descendantsmainly Native Indians Which of these species would you expect to have the lowest standard entropy (S)? a. CH4(g) b. H2O(g) c. NH3(g) d. HF(g) Now respond from the friends point of view. Using three verbs of influence and the infinitive, respond to the advice you just gave. You can say things like 'I prefer to move to Hollywood' The Peppered moth is white with black spots, which helps it blend in with the bark on beech trees. The burning of coal in Great Britain caused many beech trees to become black with soot. Over time, the Peppered moth became all black in order to blend in with the new bark color. What type of example is this? homeostasis metabolism organization adaptation Multiple-Choice Questions1. In 1995, Diana read 10 English books and 7 French books. In 1996, she read twice as many French books as English books. If 60% of the books that she read during the 2 years were French, how many English and French books did she read in 1996?(A) 16(B) 26(0) 32(D) 48 A string is stretched and fixed at both ends, 200 cm apart. If the density of the string is 0.015 g/cm, and its tension is 600 N, what is the wavelength (in cm) of the first harmonic? A cross-sectional view of a log shows a concentric pattern. Which part of the stem gives rise to this pattern? The business case for why companies should act in a socially responsible manner includes: Select one: a. It generates internal benefits including employee recruiting, workforce retention, training, and improved worker productivity b. It reduces the risk of reputation-damaging incidents c. It is in the best interest of shareholders and offers potential for increased buyer patronage d. All of the above Which Supreme Court case resulted in due process rights for adults being available for juveniles accused of crimes?Hazelwood v. KuhlmeierTinker v. Des MoinesIn re GaultBrown v. Board of Education The Hirt & Block mutual fund has assets of $147 million, liabilities of $7 million and 7 million shares outstanding. The shares trade at $21.60 per share. What is the percentage load fee? Correct Inc. is a publicly traded firm with 100 million diluted shares outstanding trading at $37.50 per share. The company has $1 billion of debt outstanding with a cost of debt at 6.5% at a marginal tax rate of 40%. The company has $100 million of cash on its balance sheet. What is the enterprise value of Correct Inc. A circle has a circumference of 153.86153.86153, point, 86 units.What is the radius of the circle? What are examples of career fields Skills USA prepares students for? Check all that apply.health scienceO educationagricultureconstructionmanufacturingtransportationinformation technologypublic safety Kate's Diner offers one breakfast item, a breakfast special. The market price for this meal is $5. At her profit-maximizing level of output, Kate's average variable cost is $4 per meal. Her average total cost is $6 per meal. Since the market is perfectly competitive, Kate should ________. Kevin has a BMI of 28.5. How many calories should he eliminate from his diet every day to achieve weight loss? a.600 calories b.400 calories c.100 calories d.200 calories e.300 calories "An individual who is 25 years from retirement has $500,000 to invest today. He is risk tolerant and is looking to withdraw $80,000 per year once he retires. Which asset allocation is BEST for this client?"