Preliminary preformulation studies for a new candidate drug molecule does not include one of these
A. Identity
B. Formula and weight
C. pharmacological activity
D. Pilot scale up
Answer:
Pilot scale up
Explanation:
Preformulation studies are carried out on candidate drug molecules that show sufficient pharmacological promise in animal model(pharma approach).
It involves preliminary study of the properties of a drug which is considered a potentially active ingredient against a particular disease condition.
Scale-up is the term used to refer to the increase in the batch size of a product. This is only done after a drug has been proven successful against the target disease after extensive pilot studies.
Scale-up is the last operation carried out when a drug has passed through all stages. It is not included in preliminary preformulation studies
Question 9 of 25
How many hydrogen atoms are in a molecule of table sugar (C12H,2011)?
O A. 12
B. 45
C. 11
D. 22
SUBMIT
D.22
is my answer than welcome
For the following reaction, 15.4 grams of chlorine gas are allowed to react with 49.6 grams of sodium iodide. chlorine (g) sodium iodide (s) sodium chloride (s) iodine (s) What is the maximum amount of sodium chloride that can be formed
Answer:
19.3 g of NaCl can be produced
Explanation:
We state the reaction:
Cl₂ (g) + 2NaI (s) → 2NaCl (s) + I₂ (s)
We need to determine limiting reagent:
15.4 g . 1mol /70.9g = 0.217 moles of chlorine
49.6 g . 1mol / 149.89g = 0.331 moles of NaI
Ratio is 1:2. 1 mol of chlorine reacts to 2 moles of NaI
0.217 moles may react to (0.217 . 2)/1 = 0.434 moles of NaI
It is ok to say the NaI is the limting reactant because we need 0.434 moles of it and we only have 0.331.
Ratio is 2:2.
0.331 moles of NaI can produce 0.331 moles of NaCl
We convert mass to moles: 0.331 mol . 58.45g /mol = 19.3 g
Calculate the number of moles of sulfuric acid in the total volume you used in the lab (i.e., 8.00 mL). Hint: Use the methodology of Question (1) above for finding out the molarity of the concentrated sulfuric acid first from its density (1.84 g/mL) and concentration (98.0% w/w), then find the number of moles. Show full work.
Answer:
0.147 mol
Explanation:
Step 1: Calculate the volumetric concentration (Cv)
We will use the following expression.
Cv = Cg × ρ
Cv = 98.0 g%g × 1.84 g/mL = 180 g%mL
Step 2: Calculate the molarity of sulfuric acid
We will use the following expression.
M = mass solute / molar mass solute × liters of solution
M = 180 g / 98.08 g/mol × 0.100 L = 18.4 M
Step 3: Calculate the moles of solute in 8.00 mL of solution
8.00 × 10⁻³ L × 18.4 mol/L = 0.147 mol
When solid Ni metal is put into an aqueous solution of Pb(NO3)2, solid Pb metal and a solution of Ni(NO3)2 result. Write the net ionic equation for the reaction.
Answer:
[tex]Pb^{2+}(aq)+Ni(s)\rightarrow Ni^{2+}(aq)+Pb(s)[/tex]
Explanation:
Hello there!
In this case, according to the given information, it turns out firstly necessary for us to write the complete molecular equation as shown below:
[tex]Pb(NO_3)_2(aq)+Ni(s)\rightarrow Ni(NO_3)_2(aq)+Pb(s)[/tex]
Now, we can separate the nitrates in ions as they are aqueous to obtain:
[tex]Pb^{2+}(aq)+2(NO_3)^-(aq)+Ni(s)\rightarrow Ni^{2+}(aq)+2(NO_3)^-(aq)+Pb(s)[/tex]
And then, we cancel out the nitrate ions as the spectator ones, for us to obtain the net ionic equation:
[tex]Pb^{2+}(aq)+Ni(s)\rightarrow Ni^{2+}(aq)+Pb(s)[/tex]
Best regards!
1: When salt is mixed into water it becomes a. element
Water molecules pull the sodium and chloride ions apart, breaking the ionic bond that held them together. After the salt compounds are pulled apart, the sodium and chloride atoms are surrounded by water molecules, as this diagram shows. Once this happens, the salt is dissolved, resulting in a homogeneous solution.
hope this helps you
have a nice day:)
The following compound can be identified as
Answer:
3: Lactone
Explanation:
Lactones are defined as carboxylic esters that contain the structure (−C(=O)−O−) which is essentially showing that an ester has now become part of the chemical structure of the ring.
Thus, looking at the question, it has the structure as defined in Lactones.
Thus, we can say that the compound is a Lactone.
what is the hybridisation of the central carbon in CH3C triple bonded to N
Explanation:
the carbon would be sp3 hybridized, and it doesn't matter which carbon, since either of them have a full octet
which of these statements is true about planets? Planets
A. revolve around the sun
B. are spherical in shape
C. rotate in its axis
D. all of the above
Answer:
D. all of the above
Explanation:
A and C are verified by Keplar's laws of planetary motion.
B is verified by the equatorial and polar aces of the Planet.
Answer:
c
Explanation:
they dont have to orbit the sun specifically and are commonly more ovoid than spherical
Identify the compound in the following group that is most soluble in water. Match the words in the left column to the appropriate blanks in the sentences on the right. ResetHelp Of the three compounds butanoic acid, butane, and butanone, the one that is most soluble in water is . This is because its functional group can form the intermolecular forces with polar water.
butanoic acid strongest hydrocarbon butanone butane alcohol carboxylic acid What carboxylic acid is found in each of the following substances? Drag the appropriate descriptions to their respective bins. Reset rancid butter stinging red ants Methanoic acid Butanoic acid Propanoic acid Ethanoic acid Review Co Draw the structure of methyl butanoate, Draw the molecule on the canvas by choosing buttons from the Tools (for bonds and charges), Atoms toolbars. H: 129 uxo com H o с + N 1 0 S a CH Br р
Answer:
Following are the responses to the given points:
Explanation:
For question 1:
Butanoic acid, butane, and butanone are also the three chemicals most dissolve in water. Its intermolecular force forces are produced by carboxylic acid functional groups with water.
For question 2:
Butanoic acid is a rancid buffer.
Methanoic acid is responsible for the stinging red ants
For question 3:
Methyl butanoate's chemical structure.
A second-order reaction has a half-life of 12 s when the initial concentration of reactant is 0.98 M. The rate constant for this reaction is ________ M-1s-1. A) 12
Answer: 0.085 (Ms)⁻¹
Explanation: Half life = 12 s
is the initial concentration = 0.98 M
Half life expression for second order kinetic is:
k = 0.085 (Ms)⁻¹
The rate constant for this reaction is 0.085 (Ms)⁻¹ .
Fill in the left side of this equilibrium constant equation for the reaction of acetic acid HCH3CO2 with water.
______ = Ka
Answer:
The left side equation is:
[tex]Ka = \frac{[CH_{3}COO^{-}] [H_{3}O^{+}]}{[HCH_{3}COO] [H_{2}O]}[/tex]
Explanation:
For the reaction of acetic acid HCH3CO2 with the water, The equilibrium constant equation is
[tex]HCH_{3}COO + H_{2}O \rightleftharpoons CH_{3}COO^{-} + H_{3}O[/tex]
The left side of this equilibrium constant equation will be written as shown below:
[tex]Ka = \frac{[CH_{3}COO^{-}] [H_{3}O^{+}]}{[HCH_{3}COO] [H_{2}O]}[/tex]
2. For each of the ionic compounds in the table below, name the compound and explain the rule that you
used in formulating your name for the compound.
Name:
Rule for naming compound:
-PbF4
-NH4NO3
-Li2S
Answer:
2
Explanation:
Lead(|V) fluoride
Ammonium Nitrate
Lithium sulfide
For the rules, I don't know what you were taught. I just do it intuitively since I have done so much chemistry.
The first one the roman numerals represents the charge of the lead which much match the 4- charge from the 4 fluorides.
The second one is just two polyatomic ions which you just have to remember.
The last one is the typical ionic compound naming technique i guess.
Write a complete, balanced equation for the following reactions:
e) The heating of sodium carbonate (teachers note: produces sodium oxide and carbon dioxide).
f) chromium (III) hydroxide plus sulfuric acid (teachers note: You figure out products).
g) aluminum metal plus chlorine gas (teachers note: produces aluminum chloride).
Please explain as well, thanks!
Answer:
Solution given:
e) The heating of sodium carbonate to produces sodium oxide and carbon dioxide
Solution given:
Balanced chemical equation:
[tex]\boxed{\bold{\green{Na_{2}CO_{2} +heat \rightarrow Na_{2}O +CO_{2}}}}[/tex]
when sodium carbonate is heated it decomposed and form sodium oxide and carbon dioxide
f) chromium (III) hydroxide plus sulfuric acid
Balanced chemical equation:
[tex]\boxed{\bold{\green{2Cr(OH)_{3}+ 3H_{2}SO_{4} → Cr_{2}(SO_{4})_{3} + 6H_{2}O}}}[/tex]
When chromium (III) hydroxide react with sulfuric acid double displacement takes place and forms produce chromium(III) sulfate and water.
g) aluminum metal plus chlorine gas
[tex]\boxed{\bold{\green{2Al(s) + 3Cl_2(g) \rightarrow 2AlCl_2 }}}[/tex]
When aluminum metal is added to chlorine gas Combination reaction takes place and forms aluminum chloride.
e) The heating of sodium carbonate to produces sodium oxide and carbon dioxide
Solution given:
Balanced chemical equation:
[tex]\boxed{\bold{\green{Na_{2}CO_{2} +heat \rightarrow Na_{2}O +CO_{2}}}}[/tex]
when sodium carbonate is heated it decomposed and form sodium oxide and carbon dioxide
f) chromium (III) hydroxide plus sulfuric acid
Balanced chemical equation:
[tex]\boxed{\bold{\green{2Cr(OH)_{3}+ 3H_{2}SO_{4} → Cr_{2}(SO_{4})_{3} + 6H_{2}O}}}[/tex]
When chromium (III) hydroxide react with sulfuric acid double displacement takes place and forms produce chromium(III) sulfate and water.
g) aluminum metal plus chlorine gas
[tex]\boxed{\bold{\green{2Al(s) + 3Cl_2(g) \rightarrow 2AlCl_2 }}}[/tex]
When aluminum metal is added to chlorine gas Combination reaction takes place and forms aluminum chloride.
You have 10 pounds of egg whites. You need 6oz to make one serving of cosomme. How many servings can you make?
Answer:
I think you can make 26, hope this helped.
Explanation:
Based on the electron configuration of the two atoms, predict the ratio of metal cationic (+) atom to nonmetal anionic (-) atom in the compound.
Lithium 1s^22s^1
Chlorine 1s^22s^22p^6 3s^23p^5
Answer:
Option A. 1:1
Explanation:
From the question given above, the following data were obtained:
Li => 1s² 2s¹
Cl => 1s² 2s²2p⁶ 3s²2p⁵
Lithium (Li) will form compound with Cl by losing 1 electron as shown below:
Li —> Li⁺ + e¯ ..... (1)
Cl on the other hand will accept 1 electron from Li to form the chloride ion, Cl¯ as shown below:
Cl + e¯ —> Cl¯ ...... (2)
Combining equation 1 and 2, we have:
Li + Cl + e¯ —> Li⁺ + Cl¯ +
Cancel e¯ from both side
Li + Cl —> Li⁺Cl¯
Thus, the ratio of metallic cation (+) to non-metallic anion (-) in the compound is 1:1
The product of the following reaction is
``````````````````````````````````
Consider the reaction of 2-chloro-2-methylpentane with sodium iodide.
Assuming no other changes, how would it affect the rate if one simultaneously doubled the concentration of 2-chloro-2-methylpentane and sodium iodide?
A) No effect.
B) It would double the rate.
C) It would triple the rate.
D) It would quadruple the rate.
E) It would increase the rate five times.
Answer:
Explanation:
The reaction between 2 chloro- 2 methyl pentane and sodium iodide takes place through SN2 mechanism . iodide ion is the nucleophile which attacks the substrate . The rate of such reaction depends upon concentration of both the nucleophile and the substrate .
Hence rate of reaction will be increased by 2 x 2 = 4 times.
option D ) is correct.
Explanation:
The given reaction represents the reaction between a tertiary alkyl halide that is 2-chloro-2-methylpentane and a nucleophile that is NaI.
This reaction favors SN1 mechanism which has order one.
So, the given reaction follows first-order kinetics.
For a first-order reaction, the rate law is:
rate =k [A]
That means the rate of the reaction is dependent on the concentration of reactants.
So, when the concentration of the reactant is doubled then, the rate of the reaction is also doubled.
Among the given options the correct answer is option B) It would double the rate.
X = atomic number - number of core electrons
Which of the following explains the identity of X and its trends down a group?
A. X is the effective nuclear charge, and it remains constant down a group.
B. X is the screening constant, and it remains constant down a group.
C. X is the effective nuclear charge, and it increases down a group.
D. X is the screening constant, and it increases down a group.
Based on the expression given in the question, X is the effective nuclear charge, and it increases down a group.
What is an effective nuclear charge?Effective nuclear charge is the net nuclear charge that an electron in an atom experiences, after subtracting the nuclear charge shielded by other electrons.
The effective nuclear charge is denoted by Zeff and can be calculated by subtracting the number of shielding electrons from the atomic number.
Therefore, based on the expression given in the question, X is the effective nuclear charge, and it increases down a group.
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Hydrogen gas and fluorine gas will react to form hydrogen fluoride gas. What is the standard free energy change for this reaction
Answer:
[tex]\Delta G=-541.4kJ/mol[/tex]
Explanation:
Hello there!
In this case, according to the given information, it turns out firstly necessary to write out the described chemical reaction as shown below:
[tex]H_2+F_2\rightarrow 2HF[/tex]
Now, we set up the expression for the calculation of the standard free energy change, considering the free energy of formation of each species, specially those of H2 and F2 which are both 0 because they are pure elements:
[tex]\Delta G=2\Delta G_f^{HF}-(\Delta G_f^{H_2}+\Delta G_f^{F_2})\\\\\Delta G=2*-270.70kJ/mol-(0kJ/mol+0kJ/mol)\\\\\Delta G=-541.4kJ/mol[/tex]
Regards!
How did the work of Dmitri Mendeleev differ from that of John Newlands in the development of the periodic table?
Answer: Mendeleev predicted elements that would later be discovered.
Which does not result in deviations from linearity in a Beer's law plot of absorbance versus concentration?a. light losses at the cell interface b. all are sources of nonlinearity c. stray radiation d. equilibrium between different forms of the analyte e. a wide bandwidth relative to the width of the absorption band
Answer:
a
Explanation:
Beer-Lambert Law shows the relationship between the factors affecting the absorbance of a sample in relation to the concentration. These factors are:
the concentration c, path length (l), and the molar absorptivity (ε).
As a result, more radiation is assimilated as the concentration rises, and the absorbance rises as well. However, the longer the path length, the increase in the number of molecules and the higher the absorbance.
Thus, the straight-line equation for Beer-Lambert's law is:
A = εcl
From the above explanation, the option that doesn't relate to the deviations from linearity of Beer's law plot is in Option (a).
5) When heated in a flame, the element Indium emits electromagnetic radiation with a distinctive indigo blue
color (the name indium is derived from the word indigo). The emitted photons that give rise to this
color
have energies of 4.405 x 10^-19J. Calculate the wavelength of this radiation in nanometers.
Answer:
[tex]\lambda=451nm[/tex]
Explanation:
Hello there!
In this case, according to the given information, it turns out possible for us to solve this problem by using the following equation, defined in terms of energy, Planck's constant, wavelength and speed of light:
[tex]E=\frac{hC}{\lambda }[/tex]
Thus, we solve for the wavelength as shown below:
[tex]\lambda=\frac{hC}{ E}[/tex]
And finally plug in the energy, Planck's constant and speed of light to obtain:
[tex]\lambda=\frac{6.6261 x 10^{-34} m^2 kg / s*3x10^8m/s}{4.405x10^{-19}m^2kg/s^2}\\\\\lambda=4.513x10^{-7}m*\frac{1nm}{10^{-9}m} \\\\\lambda=451nm[/tex]
Regards!
How many atom in protons
Answer:
Its atomic number is 14 and its atomic mass is 28. The most common isotope of uranium has 92 protons and 146 neutrons. Its atomic number is 92 and its atomic mass is 238 (92 + 146).
Which type of element is almost always found as a single atom in nature?
O A. Alkaline earth metal
O B. Halogen
c. Noble gas
D. Oxygen family element
Noble gas elements are almost always found as a single atom in nature.
What is inert gas?An inert gas is a gas that does not undergo chemical reactions under a set of given conditions. The noble gases often do not react with many substances and were historically referred to as inert gases.
All noble gases have the maximum number of electrons in their outer shell; i.e. 2 electrons for helium and 8 for the other five.
Noble gases are monoatomic, which means they exist as single atoms. This is because of their electronic stability.
Thus, noble gas elements are almost always found as a single atom in nature. Hence, option C is correct.
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what are the products in a chemical equation located?
Answer:
they are the end results so they are after the yields symbol
Explanation:
1.0 g of a compound A is prepared in 100 mL of water, and then extracted with 50 mL of ether. After the extraction, 0.25 g of the compound was recovered from the ether layer. What is the partitioning coefficient([A]ether/[A]water) for this compound in the system used?a. 4.0b. 3.0c. 1.5d. 0.75e. 0.25f. 0.67
Answer:
uh 2
Explanation:
Its 2 cause uh 2 sounds about right
To solve this we must know the concept behind partition coefficient. The partitioning coefficient for this compound in the system used is 0.67. Therefore, the correct option is option F.
What is partition coefficient?The ratio of a solute's concentrations in two solids, immiscible liquids, or barely miscible liquids when they are in equilibrium throughout the interface connecting them is called partition coefficient.
In fundamental chemistry, partitioning is utilized to separate components in procedures like chromatography. Partitioning is a crucial factor in the distribution of chemicals and medications between the blood and bodily tissues in the field of pharmacology.
Mathematically,
partition coefficient= concentration of the solute in stationary phase/concentration of the solute in mobile phase
partition coefficient={(0.25 /M)÷50}÷{(1.0/M)÷100 }
=0.005÷0.01
=0.67
Therefore, the correct option is option F.
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Oleic acid and elaidic acid are isomeric alkenes.
a. True
b. False
Answer:
False
Explanation:
Because Elaidic acid is an isomer of oleic acid. I really hope this helps you.
A student pours a few drops of vinegar onto limestone and it starts bubbling. What kind of reaction is this? How does it relate to chemical weathering, monuments and statues?
Answer:
The correct answer is - acid-base reaction or chemical weathering.
Explanation:
Vinegar is an acid that dissolves a material that is commonly found and known as calcium carbonate present in the limestone. When these two, vinegar mix with calcium carbonate of the limestone, the atoms in the acetic acid and the calcium carbonate come apart and rearrange in different ways to make new chemicals.
This rearrangement results in the release of carbon dioxide as a stream of bubbles. It is a form of weathering called chemical weathering and many monuments are based on rocks that have limestones in their composition and acid rain work similar to vinegar.
An experimental drug, D, is known to decompose in the blood stream. Tripling the concentration of the drug increases the decomposition rate by a factor of nine. Write the rate law for decomposition of D.
Answer:
R=k[D]^2
Explanation:
Given that it is a decomposition reaction;
D--->product
Hence;
The rate law is;
R= k[D]^x ----(1)
When we triple the concentration of D we have;
[D]' = [3D]^x
Therefore;
R'= 3R
R'= k[D]'----(2)
Hence dividing (1) by (2);
R/R' = k[D]^x/k[D]'
R/9R = k[D]^x/k[3D]^x
1/9 = 1/3^x (take inverse of both sides)
9 = 3^x
3^2 = 3^x
x= 2
Hence the rate law;
R=k[D]^2
